Evidence map›Paper›PMID 42129556›Full record

ArticleNature2026

Sustaining microglial reparative function enhances stroke recovery.

Jun Tsuyama, Seiichiro Sakai, Kumiko Kurabayashi, Ayaka Nakamura, Eri Tanaka, Yuichiro Hara, Ito Kawakami, Makoto Tsuda, Takahiro Masuda, Marco Prinz and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jun TsuyamaDepartment of Neuroinflammation and Repair, Medical Research Laboratory, Institute of Science Tokyo, Tokyo, Japan. tsuyama.j.662a@m.isct.ac.jp.ORCID http://orcid.org/0009-0006-6186-8294
Seiichiro SakaiDepartment of Neuroinflammation and Repair, Medical Research Laboratory, Institute of Science Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-7591-1621
Kumiko KurabayashiDepartment of Neuroinflammation and Repair, Medical Research Laboratory, Institute of Science Tokyo, Tokyo, Japan.
Ayaka NakamuraDepartment of Neuroinflammation and Repair, Medical Research Laboratory, Institute of Science Tokyo, Tokyo, Japan.
Eri TanakaDepartment of Neuroinflammation and Repair, Medical Research Laboratory, Institute of Science Tokyo, Tokyo, Japan.
Yuichiro HaraResearch Center for Genome and Medical Sciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Ito KawakamiLaboratory for Neuropathology, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Makoto TsudaDepartment of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0003-0585-9570
Takahiro MasudaDivision of Molecular Neuroimmunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0003-3687-452X
Marco PrinzInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-0349-1955
Hideya KawajiResearch Center for Genome and Medical Sciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.ORCID http://orcid.org/0000-0002-0575-0308
Takashi ShichitaDepartment of Neuroinflammation and Repair, Medical Research Laboratory, Institute of Science Tokyo, Tokyo, Japan. shichita-tk@cmn.tmd.ac.jp.ORCID http://orcid.org/0000-0003-1110-1926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurological symptoms after brain injury can remain as lifelong detrimental sequelae because most of the spontaneous recovery response disappears within a few months after the injury

Indexed as

MicrogliaRecovery of FunctionStrokeAnimalsBrainChromatinGene Expression RegulationMaleMiceOligonucleotides, AntisenseTranscription FactorsYY1 Transcription FactorChromatinOligonucleotides, AntisenseTranscription FactorsYY1 Transcription Factor

Identifiers

PMID42129556

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.