Evidence map›Paper›PMID 42129461›Full record

ArticleScientific reports2026

Impact of shape modification of cobalt-ferrite nanoparticles on their magnetic and magnetothermal properties for magnetic hyperthermia.

Ľuboš Nagy, Adriana Zeleňáková, Pavol Hrubovčák, Žaneta Fabriciová, Michael Barutiak, Dominik Volavka, Tomáš Samuely, Maksym Lisnichuk, Ana Mraković, Dominika Zákutná and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ľuboš NagyInstitute of Physics, Faculty of Science, P.J. Šafárik University, Park Angelinum 9, Košice, 04001, Slovakia.
Adriana ZeleňákováInstitute of Physics, Faculty of Science, P.J. Šafárik University, Park Angelinum 9, Košice, 04001, Slovakia. adriana.zelenakova@upjs.sk.
Pavol HrubovčákInstitute of Physics, Faculty of Science, P.J. Šafárik University, Park Angelinum 9, Košice, 04001, Slovakia.
Žaneta FabriciováInstitute of Physics, Faculty of Science, P.J. Šafárik University, Park Angelinum 9, Košice, 04001, Slovakia.
Michael BarutiakInstitute of Physics, Faculty of Science, P.J. Šafárik University, Park Angelinum 9, Košice, 04001, Slovakia.
Dominik VolavkaInstitute of Physics, Faculty of Science, P.J. Šafárik University, Park Angelinum 9, Košice, 04001, Slovakia.
Tomáš SamuelyInstitute of Physics, Faculty of Science, P.J. Šafárik University, Park Angelinum 9, Košice, 04001, Slovakia.
Maksym LisnichukInstitute of Physics, Faculty of Science, P.J. Šafárik University, Park Angelinum 9, Košice, 04001, Slovakia.
Ana MrakovićDepartment of Theoretical Physics and Condensed Matter Physics, VINČA Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia.
Dominika ZákutnáDepartment of Inorganic Chemistry, Faculty of Science, Charles University, Hlavova 2030/8, Prague 2, 128 00, Czech Republic.
Zuzana JendželovskáInstitute of Biology and Ecology, Faculty of Science, P.J. Šafárik University in Košice, Šrobárova 2, Košice, 04154, Slovakia.
Ivana BarčákováInstitute of Biology and Ecology, Faculty of Science, P.J. Šafárik University in Košice, Šrobárova 2, Košice, 04154, Slovakia.
Rastislav JendželovskýInstitute of Biology and Ecology, Faculty of Science, P.J. Šafárik University in Košice, Šrobárova 2, Košice, 04154, Slovakia.

Funding

Recovery and Resilience Plan EU for Slovakia No. 09I03-03-V04-00177
6 · The paper itself

Abstract

Cobalt-ferrite magnetic nanoparticles (MNPs) exhibiting three distinct morphologies: spherical, cubic, and octopod-like, with perfect shape resolution and a very narrow size distribution, were successfully synthesised by the thermal decomposition method. The influence of particle shape on the structural, magnetic, and magneto-thermal properties was systematically investigated. The magneto-thermal performance was evaluated under AC fields with varying amplitudes and frequencies and quantified using the SAR and ILP parameters. A pronounced dependence of heating efficiency on particle morphology was observed. Cubic nanoparticles exhibited the highest magneto-thermal performance, reaching SAR values up to 411 W/g at applied field ∼20 kA/m and 728 kHz, whereas spherical nanoparticles showed negligible heating, and octopod particles exhibited intermediate performance. These differences are interpreted within the framework of linear response theory, highlighting the roles of effective magnetic anisotropy and interparticle interactions in governing the magneto-thermal response. The response of A549 and HT-29 cancer cells to cobalt-ferrite nanoparticles was found to be strongly concentration-dependent. At a concentration of 100 µg/mL, cubic nanoparticles exhibited the weakest inhibitory effect, while lower concentrations were well tolerated without a significant morphology-dependent effect. Overall, the results underline the importance of morphology control in the design of efficient and biocompatible cobalt-ferrite nanoparticles for magnetic hyperthermia applications.

Indexed as

Magnetic hyperthermiaMagnetic nanoparticlesOctopodsShape-controlled synthesis

Identifiers

PMID42129461
PMCPMC13365480

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.