Evidence map›Paper›PMID 42129433›Full record

Trial reportScientific reports2026

Electromyography of the stapedius muscle via a retrofacial approach and electrically evoked stapedius reflex during cochlear implant surgery: a prospective bicentric study.

Orlando Guntinas-Lichius, Dirk Arnold, Gerd Fabian Volk, Daniela Korth, Daniel Richter, Rene Aschenbach, Fritz Schneider, Thore Schade-Mann, Philipp Gamerdinger, Jose Luis Vargas Luna and 2 more

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Orlando Guntinas-LichiusDepartment of Otorhinolaryngology, Facial-Nerve-Center, Jena University Hospital, Jena, Germany. orlando.guntinas@med.uni-jena.de.ORCID http://orcid.org/0000-0001-9671-0784
Dirk ArnoldDepartment of Otorhinolaryngology, Facial-Nerve-Center, Jena University Hospital, Jena, Germany.
Gerd Fabian VolkDepartment of Otorhinolaryngology, Facial-Nerve-Center, Jena University Hospital, Jena, Germany.
Daniela KorthDepartment of Otorhinolaryngology, Facial-Nerve-Center, Jena University Hospital, Jena, Germany.
Daniel RichterDepartment of Otorhinolaryngology, Facial-Nerve-Center, Jena University Hospital, Jena, Germany.
Rene AschenbachDepartment of Radiology, Jena University Hospital, Jena, Germany.
Fritz SchneiderDepartment of Otolaryngology-Head & Neck Surgery, Hearing Research Center, University of Tübingen Medical Center, Tübingen, Germany.
Thore Schade-MannDepartment of Otolaryngology-Head & Neck Surgery, Hearing Research Center, University of Tübingen Medical Center, Tübingen, Germany.
Philipp GamerdingerDepartment of Otolaryngology-Head & Neck Surgery, Hearing Research Center, University of Tübingen Medical Center, Tübingen, Germany.
Jose Luis Vargas LunaMED-EL Medical Electronics, Innsbruck, Austria.
Anke TropitzschDepartment of Otolaryngology-Head & Neck Surgery, Hearing Research Center, University of Tübingen Medical Center, Tübingen, Germany.
Hubert LöwenheimDepartment of Otolaryngology-Head & Neck Surgery, Hearing Research Center, University of Tübingen Medical Center, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measuring the electrically evoked stapedius reflex threshold (eSRT) with electromyography (EMG) of the stapedius muscle (SM) may offer an objective approach for cochlear implant (CI) fitting. During unilateral CI surgery in 14 adult patients with single-sided deafness, a retrofacial or anterior approach were used to evaluate the feasibility of SM-EMG during acoustically and electrically elicited stapedius reflex (SR). No adverse events occurred. This neurophysiology-based method was compared with visual detection of the SR. Intraoperatively, the belly of the SM was accessed via the retrofacial approach in 11 patients and via an anterior approach in 3 patients. Objective SR determination using electrical stimulation through the CI combined with SM-EMG was feasible in 7 patients using the retrofacial approach, but in only 1 patient using the anterior approach. Overall, electrical stimulation elicited SM-EMG responses in 8 patients, whereas acoustic stimulation elicited responses in only 3 patients. When eSRT measurement via SM-EMG was possible, stimulation thresholds were equal or slightly lower than thresholds identified visually in 85% of all SR measurements. SM-EMG-based eSRT appears to be a viable approach to estimate the eSRT intraoperatively in CI users as it shows similar performance as current clinical intraoperative standard. Further investigation is needed to investigate the relationship between intraoperative SM-EMG-based eSRT and patients' comfort levels, establish correction factors, and potentially enable integration into future closed-loop smart CI devices.

Indexed as

Cochlear ImplantationCochlear ImplantsElectromyographyStapediusAdultAgedElectric StimulationFemaleHumansMaleMiddle AgedProspective StudiesReflexCochlear ImplantationElectrical StimulationElectromyographyReflexStapedius Reflex

Identifiers

PMID42129433
PMCPMC13172469

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.