Evidence map›Paper›PMID 42129428›Full record

ArticleScientific reports2026

Effects of photobiomodulation on the differentiation, viability, and migration of C2C12 myoblasts exposed to different concentrations of dexamethasone.

Alessandra Lima da Silva Martins, Tainá Caroline Dos Santos Malavazzi, Rosani Tereza de Siqueira E Silva, Claudio Teruo Kassa, Mohammadhossein Shaker, Aline Souza Silva, Cinthya Cosme Gutierrez Duran, Anna Carolina Ratto Tempestini Horliana, Sandra Kalil Bussadori, Kristianne Porta Santos Fernandes and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alessandra Lima da Silva MartinsPostgraduate Program in Medicine-Biophotonics, Nove de Julho University (UNINOVE), 235/249 Vergueiro Street, Liberdade, São Paulo, 01504-001, 01525-000, Brazil.
Tainá Caroline Dos Santos MalavazziDepartment of Stomatology, Discipline of Oral and Maxillofacial Pathology, School of Dentistry, University of São Paulo (FOUSP), São Paulo, 05508-000, SP, Brazil.
Rosani Tereza de Siqueira E SilvaPostgraduate Program in Medicine-Biophotonics, Nove de Julho University (UNINOVE), 235/249 Vergueiro Street, Liberdade, São Paulo, 01504-001, 01525-000, Brazil.
Claudio Teruo KassaPostgraduate Program in Medicine-Biophotonics, Nove de Julho University (UNINOVE), 235/249 Vergueiro Street, Liberdade, São Paulo, 01504-001, 01525-000, Brazil.
Mohammadhossein ShakerPostgraduate Program in Medicine-Biophotonics, Nove de Julho University (UNINOVE), 235/249 Vergueiro Street, Liberdade, São Paulo, 01504-001, 01525-000, Brazil.
Aline Souza SilvaPostgraduate Program in Rehabilitation Sciences, Nove de Julho University (UNINOVE), 235/249 Vergueiro Street, Liberdade, Sao Paulo, 01504-001, Brazil.
Cinthya Cosme Gutierrez DuranPostgraduate Program in Medicine-Biophotonics, Nove de Julho University (UNINOVE), 235/249 Vergueiro Street, Liberdade, São Paulo, 01504-001, 01525-000, Brazil.
Anna Carolina Ratto Tempestini HorlianaPostgraduate Program in Medicine-Biophotonics, Nove de Julho University (UNINOVE), 235/249 Vergueiro Street, Liberdade, São Paulo, 01504-001, 01525-000, Brazil.
Sandra Kalil BussadoriPostgraduate Program in Medicine-Biophotonics, Nove de Julho University (UNINOVE), 235/249 Vergueiro Street, Liberdade, São Paulo, 01504-001, 01525-000, Brazil.
Kristianne Porta Santos FernandesPostgraduate Program in Medicine-Biophotonics, Nove de Julho University (UNINOVE), 235/249 Vergueiro Street, Liberdade, São Paulo, 01504-001, 01525-000, Brazil.
Raquel Agnelli Mesquita-FerrariPostgraduate Program in Medicine-Biophotonics, Nove de Julho University (UNINOVE), 235/249 Vergueiro Street, Liberdade, São Paulo, 01504-001, 01525-000, Brazil. raquel.mesquita@gmail.com.ORCID http://orcid.org/0000-0001-5142-9526

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 302771/2025-5Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.133947/2025-00
6 · The paper itself

Abstract

Glucocorticoid-induced muscle atrophy remains a clinical concern because of its broad impact on skeletal muscle structure, metabolism, and regenerative capacity. This study examined whether photobiomodulation (PBM) could lessen the damaging effects of dexamethasone (DEXA) on C2C12 myoblasts during differentiation. Cells were exposed to 5, 10, or 200 µM DEXA and evaluated after 24, 48, and 72 h. A single PBM session was delivered using a 780-nm laser (70 mW, 1.05 J, 26.25 J/cm

Indexed as

Cell DifferentiationCell MovementDexamethasoneLow-Level Light TherapyMyoblastsAnimalsCell LineCell ProliferationCell SurvivalGlucocorticoidsInterleukin-6MiceTumor Necrosis Factor-alphaDexamethasoneGlucocorticoidsInterleukin-6Tumor Necrosis Factor-alphaatrophyC2C12dexamethasonemuscle cellsphotobiomodulation

Identifiers

PMID42129428
PMCPMC13365196

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.