ArticleScientific reports2026
Chest radiographic findings suggestive of possible sarcoidosis in patients with nephrolithiasis.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Renal involvement in sarcoidosis may manifest as hypercalcemia, hypercalciuria, nephrolithiasis, nephrocalcinosis, and other abnormalities, but is often underrecognized. This study investigated chest radiographic findings suggestive of possible sarcoidosis in patients with nephrolithiasis and compared available laboratory parameters between patients with and without such findings. This retrospective analytical cross-sectional study included patients undergoing PCNL or TUL for urinary stones at Razi Hospital (Guilan, Iran) from 2016 to 2021. Routine preoperative chest X-rays were reviewed; 1297 encounters had both a retrievable diagnostic-quality CXR and available core laboratory data. Two pulmonologists independently interpreted CXRs for findings suggestive of possible sarcoidosis and assigned Scadding stage (0-IV), each blinded to the other's assessment; discrepancies were adjudicated by a third pulmonologist. Preoperative laboratory variables (BUN, creatinine, uric acid, alkaline phosphatase, calcium, phosphorus, AST, ALT, and CBC) were extracted and compared between patients with radiographic findings suggestive of possible sarcoidosis (RFS group) and those without such findings (non-RFS group) using Mann-Whitney U tests and chi-square/Cochran-Armitage trend tests. Logistic regression was used to examine the association between elevated creatinine and RFS. Radiographic findings suggestive of possible sarcoidosis were identified in 2.5% of patients, most commonly in middle-aged men and predominantly as Scadding stage I patterns. Creatinine levels were higher in the RFS group than in the non-RFS group. Elevated creatinine was associated with RFS in unadjusted analysis but not after adjustment for age and sex. Radiographic findings suggestive of possible sarcoidosis were identified in a small subset of nephrolithiasis patients. Although higher creatinine levels were observed in this group, this finding should be interpreted cautiously. Chest radiography may help identify patients who warrant further evaluation, but prospective studies incorporating confirmatory diagnostic methods are needed to clarify the clinical significance of these findings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.