Evidence map›Paper›PMID 42129127›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Modeling Fungal and Amoebic Infections: Co-culture Approaches to Study MIF's Role in Infection-Induced Inflammatory Responses.

Swagata Ghosh, Mathan L

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Swagata GhoshDepartment of Microbiology, Aravind Medical Research Foundation, Madurai, India. swagata@aravind.org.
Mathan LDepartment of Proteomics, Aravind Medical Research Foundation, Madurai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vitro co-culture models of human cells and microbial pathogens offer a controlled system to study host-pathogen interactions. This chapter details the methods to establish such co-culture models for a fungal and an amoebic infection using two different human cell lines. Employing this experimental system allows the researcher to evaluate MIF's contribution to infection-driven host cell death and pro-inflammatory gene expression.

Indexed as

InflammationMacrophage Migration-Inhibitory FactorsMycosesCell LineCoculture TechniquesHost-Pathogen InteractionsHumansMacrophage Migration-Inhibitory FactorsCell-deathCo-cultureGene expressionInflammatory responseIn vitro infection

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.