Evidence map›Paper›PMID 42129058›Full record

ArticleHepatology international2026

The Asian Pacific Association of the Study of the Liver expert survey on artificial intelligence-assisted reporting of liver histopathology in metabolic dysfunction associated fatty liver disease.

H Elangovan, K Akbary, A Rastogi, A Wee, G Soon, L Adams, E Carr-Boyd, A Clouston, C L Cooper, W K Chan and 32 more

Erratum issuedAbstract read
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Article in Hepatology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

42 authors.

H ElangovanStorr Liver Centre, The Westmead Institute for Medical Research, Westmead Hospital, The University of Sydney, Sydney, NSW, Australia.
K AkbaryHistoIndex Pte Ltd, Singapore, Singapore.
A RastogiDepartment of Pathology, Institute of Liver and Biliary Sciences, New Delhi, India.
A WeeDepartment of Pathology, National University Hospital, Singapore, Singapore.
G SoonDepartment of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.
L AdamsMedical School, University of Western Australia, Perth, Washington, Australia.
E Carr-BoydHistopathology Department, Auckland City Hospital, Auckland, New Zealand.
A CloustonCentre for Liver Disease Research, School of Medicine (Southern), University of Queensland, Princess Alexandra Hospital, Ipswich, Australia.
C L CooperPathology Queensland, Princess Alexandra Hospital, Woolloongabba, Qld, Australia.
W K ChanGastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Y Y DanDivision of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore.
R Dela-CruzThe Medical City, Ortigas, Pasig City, Metro Manila, Philippines.
G GohDepartment of Gastroenterology and Hepatology, Singapore General Hospital, Singapore, Singapore.
S S HamidDepartment of Medicine, Aga Khan University, Karachi, Pakistan.
D Q HuangDivision of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore.
T KawaguchiDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.
H KimDepartment of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
W KimDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul National University College of Medicine, Seoul, Republic of Korea.
S U KimDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
J D JiaLiver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
C J LiuDivision of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
F LiuPeking University People's Hospital, Peking University Hepatology Institute, Infectious Disease and Hepatology Center, Peking University People's Hospital, Beijing, China.
W Q LeowGastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
M D MuthiahDivision of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore.
I NgDepartment of Pathology and State Key Laboratory of Liver Research, The University of Hong Kong, Pok Fu Lam, Hong Kong.
D PayawalDepartment of Internal Medicine, Fatima University Medical Center, Valenzuela, Philippines.
A F PanDepartment of Pathology, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia.
S PervezDepartment of Pathology, Aga Khan University, Karachi, Pakistan.
G ShihaGastroenterology and Hepatology Unit, Internal Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
T TanwandeeDivision of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand.
Y TanakaDepartment of Gastroenterology and Hepatology, Kumamoto University, Kumamoto, Japan.
L ThiyaphatDivision of Pathology, Chulabhorn International College of Medicine, Thammasat University, Pathum Thani, Thailand.
M VijDepartment of Pathology, Dr Rela Institute and Medical Center, Chennai, Tamil Nadu, India.
Y YilmazDepartment of Gastroenterology, School of Medicine, Recep Tayyip Erdoğan University, Rize, Türkiye.
F YilmazFaculty of Medicine, Department of Pathology, Ege University, Izmir, Türkiye.
M L YuHepatobiliary Division, Department of Internal Medicine, Center of Hepatitis Research, College of Medicine and Center of Metabolic Disorders and Obesity, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
K ZalataAnatomic Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
M H ZhengDepartment of Hepatology, MAFLD Research Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
J G FanCenter for Fatty Liver, Department of Gastroenterology, Shanghai Key Lab of Pediatric Gastroenterology and Nutrition, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
S K SarinDepartment of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India. shivsarin@gmail.com.
V WongDepartment of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong.
J GeorgeStorr Liver Centre, The Westmead Institute for Medical Research, Westmead Hospital, The University of Sydney, Sydney, NSW, Australia. jacob.george@sydney.edu.au.ORCID http://orcid.org/0000-0002-8421-5476

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionArtificial intelligence (AI) and digital pathology have the potential to augment liver biopsy interpretation in MAFLD in clinical practice and trials assessment. However, attitudes and barriers to its implementation have not been systematically explored.

methodsA survey focusing on conventional liver histology, digital pathology and its AI applications in MAFLD/MASH was conducted among hepatologists and liver pathologists in the Asia Pacific region.

resultsAI-assisted digital pathology is perceived to be a valuable addition to existing histological reporting in MAFLD/MASH. Defined standards for application and validation of AI models are important priorities for their implementation.

conclusionThere is consensus among clinical experts in the Asia Pacific that AI-assisted histological assessment is useful in MAFLD/MASH interpretation. However, there remain important challenges to the adoption of these technologies into routine clinical workflows.

Indexed as

Artificial IntelligenceLiverNon-alcoholic Fatty Liver DiseaseAsiaBiopsyHumansSurveys and QuestionnairesArtificial IntelligenceHistopathologyMAFLDMASH

Identifiers

PMID42129058
PMCPMC13332892

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.