ArticleMethods in molecular biology (Clifton, N.J.)2026
Silencing Host Factors with Hairpin RNA for Virus Resistance.
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants rely on a multi-layered innate immune system to defend against abiotic and biotic, with RNA interference (RNAi) serving as a core antiviral mechanism. RNAi generates small interfering RNAs (siRNAs) that direct sequence-specific degradation and translational inhibition of viral RNAs. However, conventional strategies involving insertion of viral genes into the plant genome pose potential biosafety concerns. By contrast, RNAi-mediated silencing of endogenous host susceptibility genes offers distinct advantages, especially when combined with natural recessive resistance alleles. This chapter describes a detailed protocol for hairpin RNA (hpRNA) construct design and application, providing a practical reference for researchers screening and identifying host factors required for plant virus infection.
Indexed as
Identifiers
42129031What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.