Evidence map›Paper›PMID 42128970›Full record

ReviewCurrent osteoporosis reports2026

Stimulant Medications and Bone Health.

Christine M Swanson, Julie H Wolfe, Chadi A Calarge

Abstract readReview
In one paragraph

Review in Current osteoporosis reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christine M SwansonDivision of Endocrinology, Metabolism and Diabetes, University of Colorado Anschutz, 12801 E. 17th Ave. Mail Stop 8106, Aurora, CO, 80045, USA. Christine.Swanson@CUAnschutz.edu.ORCID http://orcid.org/0000-0003-1554-0862
Julie H WolfeDepartment of Psychiatry, University of Colorado Anschutz, Aurora, CO, USA. Julie.Wolfe@CUAnschutz.edu.
Chadi A CalargeMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA. Chadi.Calarge@bcm.edu.

Funding

Fractured Schedules: Skeletal Effects of Acute and Chronic Night Shift WorkR01HL151332 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI SWANSON, CHRISTINE M · 2021 to 2025
$1.8M
National Institute of Child Health and Human Development R01HD101326NHLBI NIH HHS R01HL151332
6 · The paper itself

Abstract

purpose of reviewThis review summarizes the potential impact of stimulant medications on bone health, to raise awareness and optimize their safe use. RECENT

findingsStimulant medications can impair bone health through inadequate nutrient/calorie intake and stimulation of the sympathetic nervous system, which regulates bone metabolism. However, their use decreases fracture risk in younger populations ([Formula: see text]25 years old) with attention deficit/hyperactivity disorder (ADHD), likely through reductions in impulsivity and injury. Special care may be needed when fractures occur while using these medications, as recent data suggest psychostimulants are associated with impaired fracture healing. Prescription and non-prescription use of psychostimulants have increased. Their ultimate effect on bone health may be a balance between effective behavioral modification and adverse effects on bone metabolism related to nutrition and sympathetic activation. Future research should investigate how psychostimulants affect acquisition of peak bone mass, stability of bone mineral density (BMD) when used through mid/late-life, and fracture healing.

Indexed as

Attention Deficit Disorder with HyperactivityBone and BonesBone DensityCentral Nervous System StimulantsFractures, BoneFracture HealingHumansMethylphenidateCentral Nervous System StimulantsMethylphenidateAmphetamineAttention deficit/hyperactivity disorder (ADHD)Bone mineral density (BMD)FractureMethylphenidateStimulant medication

Identifiers

PMID42128970
PMCPMC13171699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.