Evidence map›Paper›PMID 42128955›Full record

ArticleEuropean journal of clinical pharmacology2026

Healthcare professionals' perspectives on medication adherence-supporting tools: a cross‑sectional survey in Italy.

Monia Donati, Carlotta Lunghi, Giulia Grillini, Marco Domenicali, Maria Lia Lunardelli, Veronica Pasini, Susy Milandri, Monica Mussoni, Fabio Pieraccini, Elisa Sangiorgi and 3 more

Abstract read
In one paragraph

Article in European journal of clinical pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Monia Donati *Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Carlotta Lunghi *Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy. carlotta.lunghi@unibo.it.
Giulia GrilliniDepartment of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Marco DomenicaliDepartment of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Maria Lia LunardelliGeriatric Acute Care, Orthogeriatric Unit & Center for Diagnosis of Cognitive Disorders and Dementia, IRCCS-AOUBO, Bologna, Italy.
Veronica PasiniGeneral Practitioner, AUSL Romagna, Cesena District, Cesena, Italy.
Susy MilandriLocal Health Authority of Romagna, Forlì, Italy.
Monica MussoniPharmaceutical Care Department, Local Health Authority of Romagna, Forlì, Italy.
Fabio PieracciniPharmaceutical Care Department, Local Health Authority of Romagna, Forlì, Italy.
Elisa SangiorgiDrug and Medical Devices Area, General Directorate for Personal Care, Health, and Welfare of the Emilia Romagna Region, Bologna, Italy.
Emanuel RaschiDepartment of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Valentina ColonnelloDepartment of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Elisabetta PoluzziDepartment of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMedication adherence is essential for treatment effectiveness, yet the uptake of adherence-supporting tools in routine care remains suboptimal. This study assessed Italian healthcare professionals' knowledge, perceived utility, and willingness to recommend medication adherence tools, and explored perceived barriers to their adoption.

methodsA questionnaire targeting healthcare professionals working in inpatient or outpatient settings across Italy was developed and validated by a panel of seven experts. It was anonymously distributed online between October and December 2023 to physicians, pharmacists, and nurses. The survey included open-ended and Likert-scale questions investigating use, perceived usefulness, barriers, and future willingness to recommend specific medication adherence tools. Data were analyzed using descriptive statistics, and differences by professional category were evaluated using Chi-square or Fisher's exact tests. Open-ended responses were analyzed through a multi-step conventional content analysis independently conducted by two researchers.

resultsA total of 660 healthcare professionals participated, including pharmacists (35%), nurses (26%), general practitioners (22%), geriatricians or internists (8.6%), and other medical doctors (8.5%). Overall, knowledge and recommendation regarding medication adherence tools were limited, with awareness ranging from 40.0% to 94.7% depending on the tool. Traditional tools such as pillboxes and paper diaries were more frequently used (42.1% and 26.3%, respectively) and were perceived as useful (26.7% and 22.3%). In contrast, digital tools (e.g., mobile apps, SMS reminders, electronic pillboxes) were rarely recommended and often described as unfamiliar. Patient-related barriers emerged as the most commonly reported obstacles for both traditional and digital tools.

conclusionsItalian healthcare professionals show limited familiarity with and use of medication adherence tools, particularly digital solutions. Targeted training and system-level strategies are needed to increase awareness, address perceived barriers, and promote the integration of effective adherence-supporting tools into routine care.

Indexed as

Attitude of Health PersonnelHealth Knowledge, Attitudes, PracticeHealth PersonnelMedication AdherenceAdherence InterventionsAdultCross-Sectional StudiesDigital HealthFemaleHumansItalyMaleMiddle AgedPharmacistsSurveys and QuestionnairesBarriersDigital toolsHealthcare professionalsMedication adherenceOlder adultsQuestionnaire

Identifiers

PMID42128955
PMCPMC13171734

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.