Evidence map›Paper›PMID 42128942›Full record

ArticleThe Journal of infectious diseases2026

The Conundrum of Shiga Toxin-Producing Escherichia coli O157:H7 Persistence: Evidence for Locally Persistent Lineages.

Gillian A M Tarr, William Finical, Joshua M Rounds, Anna Panek, Kirk Smith

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Gillian A M TarrDivision of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0001-7372-1034
William FinicalDivision of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Joshua M RoundsFoodborne, Waterborne, Vectorborne, and Zoonotic Diseases Section, Minnesota Department of Health, St.Paul, Minnesota, USA.ORCID 0000-0003-0736-7756
Anna PanekDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0009-0008-1635-1530
Kirk SmithFoodborne, Waterborne, Vectorborne, and Zoonotic Diseases Section, Minnesota Department of Health, St.Paul, Minnesota, USA.

Funding

Phylodynamics of Shiga Toxin-Producing Escherichia coli from Local SourcesK01AI168499 · NIAID · UNIVERSITY OF MINNESOTA · PI Gillian Tarr · 2022 to 2026
$688k
NIAID NIH HHS K01 AI168499NIAID NIH HHS K01AI168499NIHNIH/NIAID K01AI168499
6 · The paper itself

Abstract

Evidence suggests that Shiga toxin-producing Escherichia coli (STEC) strains do not persist at the farm level. We hypothesized that ecosystem-level STEC persistence occurs and contributes significantly to disease burden. We tested this by identifying locally persistent lineages (LPLs) of STEC O157:H7 in Minnesota. We identified 15 distinct LPLs, which were associated with 35.3% of reported cases in Minnesota and persisted for 1.3-8.6 years. Locally persistent lineages were associated with multiple outbreaks with Minnesota sources and no multi-state outbreaks, and LPL cases were spatially clustered. Our findings show long-term persistence in defined geographic areas, suggesting the importance of ecosystem-level persistence.

Indexed as

Escherichia coli InfectionsEscherichia coli O157AnimalsDisease OutbreaksHumansMinnesotaPhylogenydisease ecologygenomic epidemiologypersistencephylogeneticsShiga toxin-producing Escherichia coli

Identifiers

PMID42128942
PMCPMC13537136

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.