Evidence map›Paper›PMID 42128606›Full record

ArticleArchives of disease in childhood2026

Diagnostic accuracy of the index finger vein inspection ('Zhiwen') for assessing paediatric pneumonia severity.

Minh Quan Le Hoang, Cam Nhi Phan Thi, Nghia Thi Ngoc Nguyen, Nguyen Thuong, Ngoc Bao Le, Thuc Anh Ho, Dieu Thi Dang

Abstract read
In one paragraph

Article in Archives of disease in childhood, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Minh Quan Le HoangUniversity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam lhminhquan@ump.edu.vn.ORCID 0009-0000-0918-6399
Cam Nhi Phan ThiUniversity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID 0009-0005-1838-7287
Nghia Thi Ngoc NguyenUniversity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID 0009-0000-2759-8653
Nguyen ThuongUniversity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID 0000-0003-3727-020X
Ngoc Bao LeUniversity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID 0009-0006-3244-824X
Thuc Anh HoUniversity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID 0009-0006-5439-1977
Dieu Thi DangUniversity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID 0009-0008-3060-141X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the diagnostic accuracy and inter-rater reliability of the traditional index finger vein inspection ('Zhiwen') for assessing pneumonia severity in children.

designCross-sectional diagnostic accuracy study adhering to Standards for Reporting of Diagnostic Accuracy Studies 2015 guidelines.

settingA tertiary paediatric referral hospital in Ho Chi Minh City, Vietnam. PATIENTS: 406 children aged ≤3 years with clinically diagnosed pneumonia were enrolled between March and May 2024.

interventionsParticipants underwent independent, blinded assessment by a paediatrician (reference standard: WHO pneumonia classification) and traditional medicine practitioners (index test: 'Zhiwen' inspection). Veins were classified into 'Wind', 'Qi' or 'Life' bars based on distal extension.

main outcome measuresDiagnostic accuracy metrics (sensitivity, specificity, predictive values, likelihood ratios) and inter-rater reliability (Cohen's kappa (κ)).

resultsInter-rater reliability was excellent (κ=0.91; 95% CI 0.88 to 0.94). A significant graded association was observed between vein extension and pneumonia severity (p<0.001). The 'Life bar' extension was strongly associated with very severe pneumonia, demonstrating a sensitivity of 95.2% (95% CI 76.2% to 99.9%) and specificity of 96.4% (95% CI 94.0% to 98.0%). Crucially, the absence of the 'Life bar' yielded a negative predictive value (NPV) of 99.7%, effectively ruling out critical illness.

conclusionThe traditional 'Zhiwen' inspection is a reproducible and valid physical biomarker for pneumonia severity. Its high NPV suggests its potential as a rapid, no-cost adjunctive tool for risk stratification in children with established pneumonia in resource-constrained settings.

Indexed as

FingersPneumoniaVeinsChild, PreschoolCross-Sectional StudiesFemaleHumansInfantMaleObserver VariationPredictive Value of TestsReproducibility of ResultsSensitivity and SpecificitySeverity of Illness IndexVietnamEpidemiologyPaediatricsRespiratory MedicineStatistics

Identifiers

PMID42128606
PMCPMC13422111

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.