Evidence map›Paper›PMID 42128506›Full record

ArticleBMJ open2026

Performance of large language models (GPT-5.2, Gemini 3 Pro, Claude Sonnet 4.6 and Grok 4.1) on the Fellowship of The Royal College of Surgeons Urology Part A examination.

Abdul Rhaman Kafagi, Nazih Atassi, Abdul-Hadi Kafagi

Abstract readComparative Study
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abdul Rhaman KafagiFaculty of Biology Medicine and Health, The University of Manchester, Manchester, England, UK akafagi5@gmail.com.ORCID http://orcid.org/0009-0002-9991-8075
Nazih AtassiFaculty of Biology Medicine and Health, The University of Manchester, Manchester, England, UK.ORCID http://orcid.org/0009-0005-5813-708X
Abdul-Hadi KafagiDepartment of Urology, Wythenshawe Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester, England, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess and compare the performance of four contemporary frontier large language models (LLMs)-GPT-5.2 (OpenAI), Gemini 3 Pro (Google DeepMind), Claude Sonnet 4.6 (Anthropic) and Grok 4.1 (xAI)-on a simulated Fellowship of The Royal College of Surgeons Urology (FRCS(Urol)) Part A examination, evaluating overall accuracy, subspecialty-level performance, output consistency and response time.

designControlled comparative evaluation study using a standardised simulation framework with repeated independent testing runs per model.

settingAll models were accessed via their respective consumer-facing interfaces. No clinical setting or patient data were involved. Testing was conducted under uniform conditions with conversational memory disabled across all sessions.

participantsFour large language models were evaluated. No human participants were involved. Models were selected to represent the current frontier of publicly accessible LLMs from four distinct commercial developers. No models were excluded following selection.

interventionsEach model was presented with 240 FRCS (Urol) Part A single best answer questions, mapped to the Joint Committee on Intercollegiate Examinations' Urology Syllabus Blueprint (2023). A standardised prompt was delivered at the start of each session. Each model completed five independent examination runs. No fine-tuning or system-level modification was applied to any model. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was overall examination accuracy for each model, benchmarked against an indicative pass threshold for the FRCS (Urol) Part A examination. Secondary outcomes were performance across 18 individual urology subspecialty topics; response time reported as mean total and per-question elapsed time; and consistency of performance quantified by SD and 95% CIs derived from a sequential Monte Carlo sampling procedure. All outcomes were prospectively planned and fully measured as specified.

resultsThree of four models exceeded the indicative 74% pass threshold: Gemini 3 Pro (82.4%±0.9%; 95% CI 81.3 to 83.6%), Claude Sonnet 4.6 (79.3%±1.1%; 95% CI 77.9 to 80.6%) and GPT-5.2 (76.1%±2.4%; 95% CI 73.1 to 79.1%). Grok 4.1 failed (70.4%±0.6%; 95% CI 69.6 to 71.2%), with its entire CI below 74%. All models completed the assessment in under 3 min. Strong performance was observed in research methodology (90-98%) and andrology (92-98%), with the weakest results in paediatric urology (38.7-54.7%) and testicular cancer (48.2-67.3%). Substantial within-model output instability was identified across several domains, most notably GPT-5.2 in female urology (SD±22.8%) and anatomy (SD±14.2%).

conclusionsThree of four frontier LLMs achieved scores consistent with passing the FRCS (Urol) Part A examination, representing a substantial advance since ChatGPT-3.5. Aggregate accuracy alone, however, obscures important subspecialty weaknesses and output instability. LLMs should be regarded as adjunctive revision aids rather than authoritative knowledge sources and always used alongside expert-led teaching. Future work should evaluate performance on Part B and viva-style assessments.

Indexed as

Educational MeasurementFellowships and ScholarshipsLarge Language ModelsUrologyClinical CompetenceHumansArtificial IntelligenceMachine LearningMEDICAL EDUCATION & TRAININGSURGERYUROLOGY

Identifiers

PMID42128506
PMCPMC13182482

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.