Evidence map›Paper›PMID 42128410›Full record

ArticleACS synthetic biology2026

Sortase A-Mediated Farnesylation of Cdc42

Sophie Tschirpke, Nynke M Hettema, Benjamin Spitzbarth, Mark A R de Geus, Frank van Opstal, Rienk Eelkema, Liedewij Laan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS synthetic biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Sortase A-Mediated Farnesylation of Cdc42ACS synthetic biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sophie TschirpkeBionanoscience Department, Delft University of Technology, Delft 2629 HZ, The Netherlands.
Nynke M HettemaBionanoscience Department, Delft University of Technology, Delft 2629 HZ, The Netherlands.ORCID 0000-0003-1592-1710
Benjamin SpitzbarthDepartment of Chemical Engineering, Delft University of Technology, Delft 2629 HZ, The Netherlands.
Mark A R de GeusDepartment of Chemical Engineering, Delft University of Technology, Delft 2629 HZ, The Netherlands.ORCID 0000-0002-1639-5890
Frank van OpstalBionanoscience Department, Delft University of Technology, Delft 2629 HZ, The Netherlands.
Rienk EelkemaDepartment of Chemical Engineering, Delft University of Technology, Delft 2629 HZ, The Netherlands.ORCID 0000-0002-2626-6371
Liedewij LaanBionanoscience Department, Delft University of Technology, Delft 2629 HZ, The Netherlands.ORCID 0000-0002-7138-9004

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cdc42, a Rho-family GTPase, plays a pivotal role in establishing polarity in

Indexed as

AminoacyltransferasesBacterial Proteinscdc42 GTP-Binding ProteinCysteine EndopeptidasesEscherichia coliProtein PrenylationSaccharomyces cerevisiaeAminoacyltransferasesBacterial Proteinscdc42 GTP-Binding ProteinCysteine EndopeptidasesCdc42farnesylationpost-translational modificationprenylationprotein engineeringRho GTPases

Identifiers

PMID42128410
PMCPMC13288878

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.