Evidence map›Paper›PMID 42128383›Full record

ArticleThe Korean journal of internal medicine2026

Comparison between ligation-assisted and precutting endoscopic mucosal resection for small rectal neuroendocrine tumors: a CHASID study.

Sunghyeok Ryou, Yunho Jung, Dae Sung Kim, Hee Seok Moon, Hoon Sup Koo, Hyun Deok Shin, Ki Bae Bang, Kyu Chan Huh, Chungcheong-Daejeon Association for the Study of Intestinal Diseases (CHASID)

Abstract readComparative StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Korean journal of internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Sunghyeok RyouDepartment of Gastroenterology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea.
Yunho JungDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
Dae Sung KimDivision of Gastroenterology, Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.
Hee Seok MoonDivision of Gastroenterology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea.
Hoon Sup KooDivision of Gastroenterology, Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.
Hyun Deok ShinDepartment of Gastroenterology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea.
Ki Bae BangDepartment of Gastroenterology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea.
Kyu Chan HuhDivision of Gastroenterology, Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.
Chungcheong-Daejeon Association for the Study of Intestinal Diseases (CHASID)

Funding

Soonchunhyang University
6 · The paper itself

Abstract

BACKGROUND/

aimsFew studies have compared modified endoscopic mucosal resection (EMR) techniques for small rectal neuroendocrine tumors (NETs). This study evaluated the clinical outcomes of ligation-assisted EMR (EMR-L) and precutting EMR (EMR-P) for the treatment of small rectal NETs.

methodsWe retrospectively reviewed patients who underwent EMR-L or EMR-P for rectal NETs ≤ 10 mm at four university hospitals between January 2018 and December 2022. Primary outcomes were en bloc resection and complete resection rates; secondary outcomes included procedural time and complications.

resultsAmong a total of 195 rectal NETs, 143 were resected using EMR-L and 52 using EMR-P. Although the histopathologically measured lesion size (4.0 ± 1.7 mm vs. 5.2 ± 2.4 mm, p = 0.002) was larger in the EMR-P group, the presence of ulcer or depression and lesion location did not significantly differ between the two groups. The en bloc resection rate (100.0% vs. 96.2%, p = 0.070) and complete resection rate (95.8% vs. 90.4%, p = 0.140) also were not significantly different. However, EMR-L had a significantly shorter procedure time (3.9 ± 2.3 min vs. 9.8 ± 5.6 min, p < 0.001). No significant differences were observed in procedure-related bleeding, perforation, recurrence, or hospital stay between the groups.

conclusionBoth EMR-L and EMR-P achieved high en bloc and complete resection rates with favorable safety profiles. However, EMR-L was significantly faster, suggesting that it is a more time-efficient approach for small rectal NET resection.

Indexed as

Endoscopic Mucosal ResectionNeuroendocrine TumorsRectal NeoplasmsAgedFemaleHumansLigationMaleMiddle AgedOperative TimePostoperative ComplicationsRetrospective StudiesTreatment OutcomeEndoscopic mucosal resectionNeuroendocrine tumorsRecurrence

Identifiers

PMID42128383
PMCPMC13172795

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