Evidence map›Paper›PMID 42127964›Full record

ReviewThe Lancet. Global health2026

Sex-specific presentation, epidemiology, and control of schistosomiasis in women and adolescent girls.

Jane K Maganga, Amina Yussuph, Pamela S Mbabazi, Louis-Albert Tchuem Tchuenté, Amy S Sturt, W Evan Secor, Jennifer A Downs

Abstract readReview
In one paragraph

Review in The Lancet. Global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jane K MagangaMwanza Intervention Trials Unit, National Institute for Medical Research, Mwanza, Tanzania. Electronic address: janekagoli@gmail.com.
Amina YussuphDepartment of Obstetrics and Gynaecology, Bugando Medical Centre, Mwanza, Tanzania.
Pamela S MbabaziDepartment of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.
Louis-Albert Tchuem TchuentéCentre for Schistosomiasis and Parasitology, Faculty of Sciences, University of Yaoundé I, Yaoundé, Cameroon.
Amy S SturtInfectious Diseases Section, Veterans Affairs Palo Alto Health Care System, Palo Alto, California, USA; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Palo Alto, CA, USA.
W Evan SecorDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Jennifer A DownsCenter for Global Health, Weill Cornell Medicine, New York, NY, USA; Department of Medicine, Weill Bugando School of Medicine, Mwanza, Tanzania.

Funding

Genital Immune, Mucosal, and Viral Effects of Female Genital Schistosomiasis in TanzaniaR01AI168306 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jennifer Alzos Downs · 2022 to 2026
$3.1M
Post-Doctoral Fellowship Training in HIV Clinical InvestigationD43TW011826 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI Daniel W Fitzgerald, Saidi Kapiga · 2021 to 2026
$1.9M
Schistosomiasis and Women's Reproductive HealthK24AI182638 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jennifer Alzos Downs · 2024 to 2026
$611k
FIC NIH HHS D43 TW011826NIAID NIH HHS K24 AI182638NIAID NIH HHS R01 AI168306
6 · The paper itself

Abstract

Schistosomiasis presents a major public health problem for women and adolescent girls in endemic areas, particularly tropical and subtropical regions. Many sex-specific effects of schistosomiasis are due to Schistosoma haematobium, which primarily affects the genitourinary tract. Deposition of schistosome eggs in genital tissue causes female genital schistosomiasis (FGS), a chronic gynaecological condition that affects over 40 million women and girls. Women and girls living with FGS face intersecting challenges that compound its adverse effects. Disabling genital symptoms include pain, abnormal discharge, menstrual irregularities, and subfertility. These symptoms affect daily activities, impose financial burdens, and harm intimate relationships. Women and girls face stigma and isolation due to the similarity of FGS symptoms to sexually transmitted infections. Health systems in endemic areas are poorly equipped to consider, diagnose, and treat FGS, and women and girls are often excluded from schistosomiasis control strategies. Multifaceted approaches targeting schistosomiasis in women and girls are urgently needed.

Indexed as

SchistosomiasisSchistosomiasis haematobiaAdolescentAnimalsFemaleHumansSchistosoma haematobiumSex Factors

Identifiers

PMID42127964
PMCPMC13365023

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.