Evidence map›Paper›PMID 42127951›Full record

ReviewThe Lancet. Microbe2026

Diagnosis and treatment of female genital schistosomiasis.

Amy S Sturt, Bodo Randrianasolo, Jennifer A Downs, Karoline Jøker, Humphrey D Mazigo, Lisette van Lieshout, Peter Leutscher

Abstract readReview
In one paragraph

Review in The Lancet. Microbe, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amy S SturtInfectious Diseases Section, Department of Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Palo Alto, CA, USA. Electronic address: amysturt@stanford.edu.
Bodo RandrianasoloAssociation K'OLO VANONA, Antananarivo, Madagascar.
Jennifer A DownsCenter for Global Health, Weill Cornell Medicine, New York, NY, USA; Department of Medicine, Weill Bugando School of Medicine, Mwanza, Tanzania.
Karoline JøkerCentre for Clinical Research, North Denmark Regional Hospital, Hjoerring, Denmark.
Humphrey D MazigoDepartment of Parasitology and Entomology, School of Public Health, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Lisette van LieshoutLeiden University Center for Infectious Diseases Subdepartment Research, Leiden University Medical Center, Leiden, Netherlands.
Peter LeutscherCentre for Clinical Research, North Denmark Regional Hospital, Hjoerring, Denmark; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

Funding

Schistosomiasis and Women's Reproductive HealthK24AI182638 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jennifer Alzos Downs · 2024 to 2026
$611k
NIAID NIH HHS K24 AI182638
6 · The paper itself

Abstract

Schistosomiasis is a neglected tropical disease caused by infection with parasitic worms of the genus Schistosoma. These blood flukes release immunogenic eggs that can become trapped within the body and cause female genital schistosomiasis (FGS). FGS is predominant in areas endemic for urogenital schistosomiasis. FGS is challenging to diagnose with the currently available methods, especially in the low-resource areas where FGS predominantly occurs. Tailored diagnostic and therapeutic strategies are required to diagnose and treat FGS, given its association with poor reproductive health outcomes. This Series paper is the second in a series discussing unique sex-specific aspects of schistosome infections in women and girls. We summarise the global literature around diagnostic techniques and treatment strategies for FGS and introduce the concept of FGS subtypes: visual, histological, and molecular.

Indexed as

Genital Diseases, FemaleSchistosomiasis haematobiaAnimalsAnthelminticsFemaleHumansSchistosomaAnthelmintics

Identifiers

PMID42127951
PMCPMC13337214

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.