Evidence map›Paper›PMID 42127748›Full record

ReviewCurrent opinion in structural biology2026

Nuclear magnetic resonance of membrane proteins-Advances and opportunities.

Kyungsoo Shin, Tata Gopinath, Francesca M Marassi

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kyungsoo ShinDepartment of Biophysics, Medical College of Wisconsin 8701 Watertown Plank Road, Milwaukee, WI 53226-3548, USA.
Tata GopinathDepartment of Biophysics, Medical College of Wisconsin 8701 Watertown Plank Road, Milwaukee, WI 53226-3548, USA.
Francesca M MarassiDepartment of Biophysics, Medical College of Wisconsin 8701 Watertown Plank Road, Milwaukee, WI 53226-3548, USA; Department of Biochemistry, Medical College of Wisconsin 8701 Watertown Plank Road, Milwaukee, WI 53226-3548, USA. Electronic address: fmarassi@MCW.edu.

Funding

Project 4 - Mechanisms of pyrophosphate dysregulationP01AG081167 · NIA · MEDICAL COLLEGE OF WISCONSIN · PI Francesca M Marassi · 2023 to 2026
$13.0M
Membrane Protein Effectors of Pathogen Interactions With HostR35GM118186 · NIGMS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI Francesca M Marassi · 2016 to 2026
$8.5M
A 600 MHz NMR spectrometer upgrade for the Sanford Burnham Prebys Cancer CenterS10OD028716 · OD · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI MARASSI, FRANCESCA M · 2020 to 2020
$926k
NIA NIH HHS P01 AG081167NIGMS NIH HHS R35 GM118186NIH HHS S10 OD028716
6 · The paper itself

Abstract

Nuclear magnetic resonance (NMR) has a long history of addressing mechanistic questions in membrane biology. Its unique capabilities include the non-perturbing nature of isotope labels, the ability of NMR signals to provide atomic-level structural and dynamic information in complex samples, including living systems, and the ability to detect very weak binding through chemical shift changes. Solution and solid-state NMR methods are highly complementary and enable a wide range of biomolecular complexity and dynamic timescales to be analyzed. Here we describe recent advances that push the envelope of current technology and offer new opportunities for targeting membrane protein assemblies to gain fundamental human health insights.

Indexed as

Membrane ProteinsNuclear Magnetic Resonance, BiomolecularAnimalsHumansProtein ConformationMembrane Proteins

Identifiers

PMID42127748
PMCPMC13524125

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.