Evidence map›Paper›PMID 42127210›Full record

ArticleJournal of medicinal chemistry2026

Hydroxyflavone-Modified Aza-BODIPY Derivatives for Combined Photodynamic and CO Therapy against Neuroblastoma.

Supapon Kwangmettatam, Bongkot Uengwanarat, Chaiyapat Nabglang, Kingsak Mahingsadet, Pishyaporn Sritangos, Prapassara Muangsopa, Charupong Saengboonmee, Rung-Yi Lai, Anyanee Kamkaew

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Article in Journal of medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Supapon KwangmettatamSchool of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Bongkot UengwanaratSchool of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Chaiyapat NabglangSchool of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Kingsak MahingsadetSchool of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Pishyaporn SritangosSchool of Preclinical Sciences, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Prapassara MuangsopaSchool of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0009-0008-4462-0371
Charupong SaengboonmeeDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-1476-1129
Rung-Yi LaiSchool of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0002-2076-0969
Anyanee KamkaewSchool of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0003-1203-2686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxyflavone-modified aza-BODIPY derivatives were developed as metal-free photosensitizers integrating photodynamic therapy (PDT) with singlet oxygen-triggered carbon monoxide (CO) release for neuroblastoma treatment. The compounds exhibit near-infrared absorption, efficient singlet oxygen generation, and light-controlled CO release via hydroxyflavone decarbonylation. Among the series,

Indexed as

Antineoplastic AgentsBoron CompoundsCarbon MonoxideNeuroblastomaPhotochemotherapyPhotosensitizing AgentsAnimalsApoptosisCell Line, TumorHumansSinglet OxygenZebrafishAntineoplastic AgentsazaBDPBA compoundBoron CompoundsCarbon MonoxidePhotosensitizing AgentsSinglet Oxygen

Identifiers

PMID42127210
PMCPMC13224091

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.