In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
21 authors.
Lukas KochInstitute of Pharmacy, Freie Universität Berlin, Königin-Luise-Straße 2+4, 14195 Berlin, Germany.ORCID 0000-0002-6715-2784 Sandro AndreottiBioinformatics Solution Center, Institute of Computer Science, Freie Universität Berlin, Takustraße 9, 14195 Berlin, Germany.ORCID 0000-0001-7678-9720 Mario SchubertBioSupraMol Core Facility, Freie Universität Berlin, Takustraße 3, 14195 Berlin, Germany.ORCID 0000-0003-0278-4091 Elisa LiebhartDepartment of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany.
Anton M ZürbigInstitute of Pharmaceutical Biology and Phytochemistry, University of Münster, Corrensstraße 48, 48149 Münster, Germany.
Julian GatzkiInstitute of Chemistry, Martin Luther University Halle-Wittenberg, Von-Dankelmann-Platz 4, 06124 Halle (Saale), Germany.
Benjamin-Florian HempelVeterinary Centre for Resistance Research, Freie Universität Berlin, Robert-von-Ostertag-Straße 8, 14163 Berlin, Germany.ORCID 0000-0002-1998-4033 Lydia KollhoffDepartment of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Straße 3, 06120 Halle (Saale), Germany.ORCID 0009-0001-2466-9054 Barbara FeldmeyerSenckenberg Biodiversity and Climate Research Centre (SBiK-F), Georg-Voigt-Straße 14-16, 60325 Frankfurt am Main, Germany.ORCID 0000-0002-0413-7245 Martin HerzbergDepartment of Solar Materials Biotechnology (SOMA), Helmholtz Centre for Environmental Research GmbH (UFZ), Permoserstraße 15, 04318 Leipzig, Germany.ORCID 0000-0001-7746-0425 Valerie I C RebhahnInstitute of Pharmacy, Freie Universität Berlin, Königin-Luise-Straße 2+4, 14195 Berlin, Germany.
Nwet Nwet WinInstitute of Pharmacy, Freie Universität Berlin, Königin-Luise-Straße 2+4, 14195 Berlin, Germany.ORCID 0000-0002-4740-7727 Adria C LeBoeufDepartment of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.ORCID 0000-0002-2931-1510 Marat MeleshinDepartment of Enzymology, Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Straße 3a, 06120 Halle (Saale), Germany.ORCID 0000-0002-6887-0200 Fabian HerrmannInstitute of Pharmaceutical Biology and Phytochemistry, University of Münster, Corrensstraße 48, 48149 Münster, Germany.ORCID 0000-0002-2411-7671 Christian SchwiegerInstitute of Chemistry, Martin Luther University Halle-Wittenberg, Von-Dankelmann-Platz 4, 06124 Halle (Saale), Germany.ORCID 0000-0001-8327-1233 Heike Brötz-OesterheltDepartment of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany.ORCID 0000-0001-9364-1832 Andrea SinzDepartment of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Straße 3, 06120 Halle (Saale), Germany.
Mike SchutkowskiDepartment of Enzymology, Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Straße 3a, 06120 Halle (Saale), Germany.
Timo H J NiedermeyerInstitute of Pharmacy, Freie Universität Berlin, Königin-Luise-Straße 2+4, 14195 Berlin, Germany.ORCID 0000-0003-1779-7899 Simon TragustDepartment of General Zoology, Institute of Biology, Martin Luther University Halle-Wittenberg, Hoher Weg 8, 06120 Halle (Saale), Germany.ORCID 0000-0002-3675-9583 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Venom peptides are key to the evolutionary success of most venomous animals, including stinging ants. The stingless ant subfamily Formicinae is thought to rely solely on formic acid in their venoms, despite early, unsubstantiated hints of proteinaceous venom constituents. Here, we show that carpenter ants, the largest formicine genus, produce a diverse venom peptide arsenal. Mass spectrometry and transcriptomics across eight geographically distant species uncovered 35 peptides, formicitoxins, belonging to two gene families. Several formicitoxins display antifungal activity. Application to pupae delays fungal outgrowth, suggesting a role of the peptides in colony hygiene. Genome analyses revealed that formicitoxins are widespread but variable across the Formicinae. Our findings overturn the paradigm of formicine venoms as simple acid sprays and establish them as a source of bioactive peptides.
Indexed as
Antifungal AgentsAntimicrobial PeptidesAntsAnt VenomsFormatesAnimalsGene Expression ProfilingMass SpectrometryPhylogenyAntifungal AgentsAntimicrobial PeptidesAnt VenomsFormatesformic acid
Identifiers
PMID42127198
PMCPMC13170668
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
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