Evidence map›Paper›PMID 42126984›Full record

ArticleObesity facts2026

Psychosocial Outcomes of the Fast Track to Health Clinical Trial in Adolescents with Obesity.

Natalie B Lister, Louise A Baur, Megan L Gow, Eve T House, Cathy Kwok, Krista A Varady, Hiba Jebeile

Abstract read
In one paragraph

Article in Obesity facts, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natalie B ListerThe University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia, natalie.lister@sydney.edu.au.
Louise A BaurThe University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.
Megan L GowThe University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.
Eve T HouseThe University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.
Cathy KwokThe University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.
Krista A VaradyUniversity of Illinois, Department of Kinesiology and Nutrition, Chicago, Illinois, USA.
Hiba JebeileThe University of Sydney, Sydney Medical School, Westmead, New South Wales, Australia.

Funding

Mediating Role of Gut Microbiota in the Regulation of Colorectal Cancer Risk in the Context of Time-restricted Eating and Calorie RestrictionR01CA257807 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Lisa Tussing-Humphreys, Krista Amy Varady · 2021 to 2026
$5.4M
Time restricted feeding versus daily calorie restriction: Effect on body weight, metabolic risk, and the gut microbiomeR01DK128180 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI VARADY, KRISTA AMY · 2021 to 2025
$3.0M
Alternate day fasting combined with exercise for the treatment of NAFLDR01DK119783 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI VARADY, KRISTA AMY · 2019 to 2022
$1.4M
NCI NIH HHS R01 CA257807NIDDK NIH HHS R01 DK119783NIDDK NIH HHS R01 DK128180
6 · The paper itself

Abstract

introductionAdolescent obesity requires effective and accessible treatment. Intensive dietary interventions may be used as adjunctive therapy to behavioral interventions and lead to weight loss. The effects of behavioral interventions on psychosocial outcomes are mixed, and the impact of intensive interventions with shifts away from normal eating habits and social norms is not clear.

methodsAdolescents (13-17 years) with obesity and ≥1 complication participated in a 52-week RCT, conducted 2018-2023 (ACTRN12617001630303). The intervention compared a 4-week very low energy diet followed by intermittent or continuous energy restriction (48 weeks). Anthropometry and psychosocial health were assessed at baseline, weeks 4, 16, and 52 including Dutch Eating Behaviour Questionnaire (DEBQ), Rosenberg Self-Esteem Scale (RSE), Weight Bias Internalization Scale (WBIS), Body Appreciation Scale (BAS), and Depression Anxiety and Stress Scale (DASS). Intention-to-treat analysis using linear mixed models investigated changes over time between intervention groups.

resultsIn total, 141 adolescents (70 female) were enrolled and 97 (48 female) completed the intervention. There were significant reductions in external eating (DEBQ, p < 0.001), weight bias internalization (WBIS, p < 0.001), anxiety (DASS, p < 0.001), and stress (DASS, p = 0.082) and significant increases in self-esteem (RSE, p < 0.001) and body appreciation (BAS, p < 0.001) in both groups. There were increases in dietary restraint (DEBQ, p = 0.595) and decreases in emotional eating (DEBQ, p = 0.645) and depression (DASS, p = 0.381) which returned to baseline by the end of intervention. Reductions in BMI z-score were significantly associated with improvements in emotional eating (r = 0.215, p = 0.046, n = 87) and body appreciation (r = -0.235, p = 0.027, n = 88).

conclusionIntensive interventions incorporating dietary and behavioral components were associated with improvements in psychosocial health among adolescents with obesity-associated complication.

Indexed as

Adolescent obesityBody appreciationEating behavioursSelf-esteemWeight bias internalization

Identifiers

PMID42126984
PMCPMC13368243

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.