Evidence map›Paper›PMID 42126786›Full record

ArticleJournal of gastrointestinal cancer2026

Clinical Presentation and Management Outcomes of Pancreatic Cancer in African Countries: A Scoping Review.

Mohamed Daffalla Awadalla Gismalla, Moawia Mohammed Ali Elhassan, Ahmed Abd Elrahman Abdalla Abd Elrahman, Ali Yasen Mohamedahmed, Mohamed Soud Mohamed Saadeldien, Khalid Yousif Khalid Abu Aagla, Ahmed Mohammed Ali Ahmed, Walid Elhaj Abdelrahim, Anita Balakrishnan

Abstract readScoping Review
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohamed Daffalla Awadalla GismallaDepartment of Surgery, Faculty of Medicine, Al-Baha University, Al Baha, Saudi Arabia. mohadaff22@gmail.com.
Moawia Mohammed Ali ElhassanDepartment of Oncology, National Cancer Institute, University of Gezira, Wad Medani, Sudan.
Ahmed Abd Elrahman Abdalla Abd ElrahmanDepartment of Surgery, Medical City for Military and Security Services, Muscat, Oman.
Ali Yasen MohamedahmedDepartment of General Surgery, HPB Unit, University Hospital of Leicester, Leicester, United Kingdom.
Mohamed Soud Mohamed SaadeldienDepartment of Surgery, Faculty of Medicine, University of Gezira, Wad Medani, Sudan.
Khalid Yousif Khalid Abu AaglaDepartment of Surgery, Faculty of Medicine, National Ribat University, Khartoum, Sudan.
Ahmed Mohammed Ali AhmedDepartment of Surgery, Faculty of Medicine, Al Neelan University, Khartoum, Sudan.
Walid Elhaj AbdelrahimDepartment of Surgery, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Anita BalakrishnanCambridge HPB Unit, Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancreatic cancer remains one of the most lethal malignancies globally. In Africa, the burden is poorly characterized due to fragmented data and limited resources.

objectivesThis scoping review aimed to map published data on pancreatic cancer across the continent, identify reporting gaps, and highlight implications for research and policy.

methodsA systematic search was conducted across PubMed, OVID Medline, CINAHL, ERIC, and Scopus for articles published between January 1995 and June 2025. Inclusion criteria focused on clinical data, treatment modalities, and survival outcomes of pancreatic cancer in African populations.

resultsTwenty studies spanning 1995-2023,representing 26,850 patients, were identified. Research output was geographically uneven, concentrated in South Africa, Egypt, Morocco. The weighted mean age at diagnosis was 59.2 years. Primary symptoms included Jaundice, abdominal pain, and weight loss. Advanced-stage presentation dominated, with stage III-IV accounting for > 70% of reported cases. Staging data were missing for nearly 40% of the total cohort, and complete treatment pathways were reported in fewer than half of studies. Surgical resection rates remain low (< 15% in most cohorts), and access to adjuvant chemotherapy is inconsistent. Survival data were rarely available, with median overall survival is notably poor, ranged between 3 and 12 months.

conclusionPancreatic cancer in Africa is characterized by late-stage presentation and limited therapeutic options. Improving outcomes requires enhanced diagnostic infrastructure and region-specific clinical registries to guide evidence-based interventions.

Indexed as

Pancreatic NeoplasmsAfricaChemotherapy, AdjuvantHumansNeoplasm StagingSurvival RateTreatment OutcomeAfricaClinical presentationGlobal oncologyPancreatic cancerPancreatic ductal adenocarcinomaScoping reviewTreatment outcomes

Identifiers

PMID42126786

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.