Evidence map›Paper›PMID 42126696›Full record

ArticlePain and therapy2026

Cervical Erector Spinae Plane Block for Shoulder Arthroscopy: A Favorable Alternative to Interscalene Brachial Plexus Block? A Randomized Non-Inferiority Trial.

Tie-Shuai Liu, Jun Zhang, Yong-He Hu, Qian Hu, Qi-Hong Shen, Zi-Ming Zhang, Gang Chen

Abstract read
In one paragraph

Article in Pain and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Tie-Shuai Liu *Department of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Jun Zhang *Department of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Yong-He Hu *Department of Anesthesiology, Huzhou Central Hospital, Huzhou, Zhejiang, China.
Qian HuDepartment of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Qi-Hong ShenDepartment of Anesthesiology, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Zi-Ming ZhangDepartment of Neonatal Intensive Care Unit, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China. zhangziming@zju.edu.cn.
Gang ChenDepartment of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China. chengang120@zju.edu.cn.ORCID http://orcid.org/0000-0003-4262-9491

Funding

Zhejiang Province Medical and Health Science 2021KY751
6 · The paper itself

Abstract

introductionShoulder arthroscopy is associated with significant postoperative pain. Interscalene brachial plexus block (ISBPB) provides excellent analgesia but frequently causes hemidiaphragmatic paralysis (HDP) and respiratory impairment. Cervical erector spinae plane block (ESPB) has been proposed as a possible alternative approach, but its comparative efficacy, safety, and anatomical spread remain uncertain.

methodsIn this randomized non-inferiority trial, 70 patients undergoing arthroscopic shoulder surgery received cervical ESPB or ISBPB with 20 ml 0.375% ropivacaine. The primary endpoint was resting visual analog scale (VAS) pain at 6 h. Secondary outcomes included static and dynamic VAS, diaphragm ultrasound, respiratory function, handgrip strength, opioid use, adverse events, and satisfaction.

resultsThe median between-group difference in resting VAS at 6 h was 0 (range 0-1), meeting the non-inferiority margin. VAS pain scores were lower with ISBPB at 1 and 3 h at rest (p = 0.008 and p = 0.003) and at 3 and 6 h during movement (p < 0.001 and p = 0.007); however, all 95% confidence intervals for median differences were < 1, confirming non-inferiority of ESPB. Cumulative sufentanil use and rescue analgesia were similar. ESPB was associated with greater diaphragmatic excursion and thickening fraction and a lower HDP incidence (RR 0.2 post-block; 0.4 in the PACU; both p < 0.001). Respiratory declines were smaller with ESPB for FVC (5.8% vs. 14.8%; p < 0.001), FEV₁ (4.9% vs. 18.8%; p < 0.001), MIP and MEP (both p < 0.001). Handgrip strength was better maintained and Horner syndrome was less frequent (8.6% vs. 34.3%; p = 0.018). Other adverse events and patient satisfaction were similar between groups.

conclusionsIn this low-risk study population, cervical ESPB met the predefined non-inferiority criterion for postoperative analgesia compared with ISBPB and was associated with less diaphragmatic and respiratory impairment. However, cervical ESPB should not be considered risk-free, and further anatomical, dose-finding, and clinical studies are needed before any broader clinical role can be defined.

trial registrationClinicalTrials.gov identifier no. ChiCTR2200060019.

Indexed as

DiaphragmErector spinae plane blockInterscalene brachial plexus blockPostoperative painRandomized controlled trialShoulder arthroscopy

Identifiers

PMID42126696
PMCPMC13369091

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.