ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026
Patient-reported outcomes in oropharyngeal cancer: comparing two cohorts with different treatment protocols.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLong-term patient-reported outcomes (PROMs) may provide insight into the impact of advances in the treatment of oropharyngeal squamous cell carcinoma (OPSCC). The main aim of the study was to assess and compare PROMs in OPSCC patients treated during two different periods (1998-2006 vs. 2015-2021), reflecting advances in treatment strategies and developments in care.
methodsThe present study is based on data from two Swedish multicentre studies: the randomised controlled trial ARTSCAN1 (1998-2006) and the observational study NIPHNC (2015-2021). Patients received curative-intent radiotherapy as part of the ARTSCAN or NIPHNC studies. All patients completed PROMs at multiple time points up to 24 months post-treatment. PROMs were assessed using the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire EORTC QLQ-H&N35 and the Hospital Anxiety and Depression Scale HADS.
resultsA total of 363 patients were included, with 161 and 202 patients from ARTSCAN1 and NIPHNC, respectively. At baseline and at all post-radiotherapy time points, the NIPHNC cohort reported fewer symptoms and lower anxiety/depression. At 2 years, both groups showed improvement, though persistent issues like dry mouth and sticky saliva remained common.
conclusionsComparison of two treatment protocols demonstrates improvements in short- and long-term PROMs over time. Long-term salivary symptoms remain prevalent in patients with OPSCC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.