ArticleNeuroradiology2026
Meningioma versus dural metastasis: integration of T2*-DSC perfusion-derived percentage signal recovery with conventional and contemporary MRI features and clinical variables.
Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeDespite advances in neuroimaging, reliable differentiation between meningiomas and dural metastases remains challenging because of overlapping imaging features. This study aimed to differentiate these entities using T2*-weighted DSC MRI metrics, particularly percentage signal recovery (PSR), integrated with conventional/contemporary MRI features and clinical variables.
methodsThis single-center retrospective study analyzed pretreatment MRI examinations between January 2020 and 2026 in patients with meningioma or dural metastasis. Two neuroradiologists evaluated imaging variables, including three DSC perfusion parameters (nCBV, nPSR
resultsA total of 70 meningiomas from 59 patients and 54 dural metastases from 38 patients were included. There were no significant differences in age or sex (p = 0.10 and p = 1.00). There was no significant difference in the presence of the outline sign or rim-enhancing pattern (p = 0.674 and p = 0.111). History of malignancy was more frequent in dural metastasis (86.8% vs. 27.1%, p < 0.001). Multivariable analysis revealed four independent predictors: history of cancer, nPSR
conclusionThree MRI-derived features combined with the history of cancer demonstrated strong predictive performance and may aid diagnostic decision-making in challenging cases.
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