Evidence map›Paper›PMID 42126540›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Comparison of cervical sagittal alignment in normal subjects and adolescents and young adults with idiopathic scoliosis.

Lucas Chomienne, Guillaume Battesti, Thibaut Goetsch, Mikael Finoco, Emmanuelle Ferrero, Marc Khalifé, Thierry Odent, Edouard De Charnace, Sebastien Pesenti, Solène Prost and 5 more

Abstract readComparative Study
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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Lucas ChomienneUniversity of Strasbourg, Strasbourg, France. lucas.chomienne@chru-strasbourg.fr.
Guillaume BattestiUniversity of Strasbourg, Strasbourg, France.
Thibaut GoetschUniversity of Strasbourg, Strasbourg, France.
Mikael FinocoHôpital Européen Georges-Pompidou, Paris, France.
Emmanuelle FerreroHôpital Européen Georges-Pompidou, Paris, France.
Marc KhaliféHôpital Européen Georges-Pompidou, Paris, France.
Thierry OdentCentre Hospitalier Universitaire de Tours, Tours, France.
Edouard De CharnaceCentre Hospitalier Universitaire de Reims, Reims, France.
Sebastien PesentiHôpital de la Timone, Marseille, France.
Solène ProstHôpital de la Timone, Marseille, France.
Benjamin BlondelHôpital de la Timone, Marseille, France.
Federico SollaLenval Foundation, Nice, France.
Mourad Ould-SlimaneCentre Hospitalier Universitaire de Rouen, Rouen, France.
Brice IlharrebordeHôpital Robert-Debré, Paris, France.
Yann Philippe CharlesUniversity of Strasbourg, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose was to describe cervical sagittal alignment in adolescent idiopathic scoliosis (AIS) compared to a normal group of adolescents and young adults, seeking for differences by Lenke type.

methodsRadiographs of 1779 AIS patients and 1115 controls were analyzed. Lenke types were determined. Spinopelvic parameters, thoracic kyphosis (TK), lumbar lordosis and sagittal vertical axis (SVA) CAM, C2, and C7 were measured. Cervical parameters included McGregor slope, C1-C2 and McGregor-C2 lordosis, C2-C7 lordosis (subdivided into cranial and caudal arches), C7 and T1 slopes. Cervical alignment patterns were classified as lordotic, kyphotic or sigmoid shapes.

resultsLenke 1, 2, 3 and 6 curves showed decreased C2-C7 and caudal arch lordosis associated with decreased C7 and T1 slopes and TK (p < 0.001) compared to normal. Cranial cervical parameters were comparable to the normal group. Lenke 5 patients demonstrated TK, C7 and T1 slopes, and cervical alignment parameters close to the normal group. In AIS, TK correlated with caudal cervical (r = 0.76) and C2-C7 lordosis (r = 0.52), but only weakly with cranial cervical parameters.

conclusionCervical sagittal alignment compensatory changes in AIS predominantly involve the caudal cervical segment and are closely related to TK, while cranial alignment remains close to normal, supporting horizontal gaze. As opposed to other AIS types with thoracic deformity, Lenke 5 patients had no cervical compensation, and sagittal alignment was close to normal. Distinguishing normative from pathologic compensation across AIS curve types may help optimize surgical planning and restoration of TK to indirectly improve cervical alignment.

Indexed as

Cervical VertebraeScoliosisAdolescentAdultChildFemaleHumansKyphosisLordosisMaleRadiographyYoung AdultAdolescent idiopathic scoliosisCervical lordosisCervical sagittal alignmentGlobal sagittal alignmentThoracic kyphosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.