Evidence map›Paper›PMID 42126445›Full record

ArticleArchives of orthopaedic and trauma surgery2026

Rates of union and risk factors for continued nonunion following exchange nailing of tibial nonunion.

Julia C Mastracci, Benjamin Averkamp, Matthew Braswell, Ziqing Yu, Andrew T Chen, Roman M Natoli, Hassan Farooq, Hassan Mir, Jessica Rivera, Rachel B Seymour and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Julia C MastracciDepartment of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina, USA.
Benjamin AverkampDepartment of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina, USA.
Matthew BraswellDepartment of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina, USA.
Ziqing YuDepartment of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina, USA.
Andrew T ChenDepartment of Orthopaedic Surgery, University of North Carolina, Chapel Hill, North Carolina, USA.
Roman M NatoliDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Hassan FarooqDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Hassan MirFlorida Orthopaedic Institute, Tampa, Florida, USA.
Jessica RiveraDepartment of Orthopaedic Surgery,, Louisiana State University Health Science Center, New Orleans, Louisiana, USA.
Rachel B SeymourDepartment of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina, USA. Rachel.Seymour@advocatehealth.org.
Joseph R HsuDepartment of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina, USA.
Evidence-based Musculoskeletal Injury & Trauma Collaborative (EMIT)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe objective of this study was to evaluate the rate of nonunion repair success in tibia nonunions treated with exchange nailing. This retrospective cohort study was conducted across five academic Level 1 trauma centers and included 63 patients with tibia nonunions. MATERIALS AND

methodsPatients who sustained a tibia fracture (AO/OTA 42) treated with intramedullary fixation that developed a nonunion and were subsequently treated with exchange nailing were retrospectively reviewed. The primary outcome measure was nonunion repair success based on osseous union. Additional analyses included union rate by AO/OTA classification, nonunion type, implant(s) used, graft used, time from initial procedure, and infection status.

resultsAll patients sustained an AO/OTA type 42 fracture. Out of 63 patients, 47 tibias (75%) achieved osseous union after the index exchange nail procedure. The rates of nonunion revision success were similar across nonunion types and time from initial procedure until exchange nailing. There was no significant difference in union rate when infection was present. Complications included re-operation, readmission, infection, and implant failure.

conclusionsThis large, multicenter study with contemporary implants, instruments, and techniques for exchange nailing tibia nonunions demonstrates a nonunion repair success rate of 75%, consistent with the lower end of reported data in previous literature. No identifiable risk factors for failure of exchange nailing in tibia nonunions were found. LEVEL OF EVIDENCE: Level III Evidence.

Indexed as

Bone NailsFracture Fixation, IntramedullaryFractures, UnunitedTibial FracturesAdultAgedFemaleFracture HealingHumansMaleMiddle AgedReoperationRetrospective StudiesRisk FactorsExchange nailNonunionTibia exchange nailTibia nonunion

Identifiers

PMID42126445
PMCPMC13171982

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.