Evidence map›Paper›PMID 42126388›Full record

SynthesisVeterinary medicine and science2026

Are Insects a Feasible Option or Just a Hyped Promise in Ruminant Nutrition? A Systematic Review of What Has Been Done and What Lies Ahead.

Navid Ghavipanje, Manuel Gonzalez-Ronquillo, Manuela Renna, Agustín Corral-Luna, Ahmed Eid Kholif, Mohammad Hasan Fathi Nasri, Einar Vargas-Bello-Pérez

Abstract readSystematic Review
In one paragraph

Synthesis in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Navid GhavipanjeDepartment of Animal Science, Faculty of Agriculture, University of Birjand, Birjand, Iran.ORCID https://orcid.org/0000-0001-7819-0527
Manuel Gonzalez-RonquilloFacultad de Medicina Veterinaria y Zootecnia Instituto Literario 100. El Cerrillo, Universidad Autónoma del Estado de México, Toluca, Estado de México, México.ORCID https://orcid.org/0000-0003-3616-4157
Manuela RennaDepartment of Veterinary Sciences, University of Turin, Grugliasco, TO, Italy.ORCID https://orcid.org/0000-0003-4296-7589
Agustín Corral-LunaFacultad de Zootecnia y Ecología, Universidad Autónoma de Chihuahua, Chihuahua, México.ORCID https://orcid.org/0000-0002-4089-6011
Ahmed Eid KholifDepartment of Animal Sciences, North Carolina Agricultural and Technical State University, Greensboro, North Carolina, USA.ORCID https://orcid.org/0000-0003-0472-4770
Mohammad Hasan Fathi NasriDepartment of Animal Science, Faculty of Agriculture, University of Birjand, Birjand, Iran.
Einar Vargas-Bello-PérezFacultad de Zootecnia y Ecología, Universidad Autónoma de Chihuahua, Chihuahua, México.ORCID https://orcid.org/0000-0001-7105-5752

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insects have emerged as a promising sustainable feed alternative for ruminants, offering high nutrient density and potential environmental benefits in the context of growing pressures on conventional protein sources. This systematic review critically evaluates the state-of-the-art literature written in English and published in peer-reviewed journals from 2015 to 2025 on the use of insect-based feeds in ruminant nutrition, synthesising evidence from in vitro and in vivo studies, discussing their outcomes and elucidating underlying mechanisms to guide future research. Most insect species studied include black soldier fly (Hermetia illucens) larvae, housefly (Musca domestica) larvae, adult crickets (Gryllus bimaculatus), silkworm (Bombyx mori) pupae, and mealworm (Tenebrio molitor) larvae, with studies highlighting their favourable chemical composition, particularly high protein content and rich fatty acid profiles. In vitro and in vivo research, though occasionally inconsistent, shows promising effects on rumen fermentation, methane production, growth performance, product quality, and animal health. Nevertheless, inconsistent results, driven by variations in insect species, processing methods, and inclusion levels, highlight significant knowledge gaps. Challenges include non-standardised nutrient profiling, limited long-term health and performance studies, regulatory disparities, high production costs, scalability constraints, and underexplored consumer acceptance of sensory and market aspects. While insects offer opportunities for waste bioconversion and reduced ecological footprints, their integration requires targeted research into optimised feed formulations, longitudinal health studies, and robust regulatory frameworks. This review emphasises the necessity of multidisciplinary research to clarify the nutritional, environmental, and economic viability of insect-based feeds, paving the way for sustainable ruminant production systems.

Indexed as

Animal FeedAnimal Nutritional Physiological PhenomenaInsectaRuminantsAnimalsalternative feedcircular economyinsect‐derived productruminant feedingsustainability

Identifiers

PMID42126388
PMCPMC13170473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.