Evidence map›Paper›PMID 42126200›Full record

ArticleEmerging microbes & infections2026

Deletion of the D345L gene attenuates ASFV and induces protection against homologous and heterologous challenge by enhancing host innate immunity.

Xuefei Sun, Min Zheng, Nan Li, Xiaoying Jia, Teng Chen, Shoufeng Zhang, Huixian Yue, Qixuan Li, Boli Ma, Fengjie Wang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xuefei SunCollege of Veterinary Medicine, Jilin University, Changchun 130062, People's Republic of China.
Min ZhengState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Nan LiState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Xiaoying JiaCollege of Veterinary Medicine, Jilin University, Changchun 130062, People's Republic of China.
Teng ChenState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Shoufeng ZhangState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Huixian YueState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Qixuan LiState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Boli MaState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Fengjie WangState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Junnan KeState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Yiqian JiangState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Zhuo HaoState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Rongliang HuCollege of Veterinary Medicine, Jilin University, Changchun 130062, People's Republic of China.
Yanyan ZhangState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.
Faming MiaoState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Prevention & Control for African Swine Fever and Other Major Pig Diseases, Ministry of Agriculture and Rural Affairs, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African swine fever (ASF) is a highly contagious and lethal disease caused by African swine fever virus (ASFV), with a mortality rate approaching up to 100%. At present, the functions of multiple genes of ASFV remain to be elucidated. In this study, we demonstrate that pD345L is a late-expressed viral protein and localizes to the viral factory. The recombinant strain JX23-02Δ

Indexed as

African Swine FeverAfrican Swine Fever VirusImmunity, InnateViral ProteinsViral VaccinesAnimalsCytokinesGene DeletionSwineVaccines, AttenuatedVirulenceVirus ReplicationCytokinesVaccines, AttenuatedViral ProteinsViral VaccinesASFASFV JX23-02D345Linnate immunityprotective immunityvirulence gene

Identifiers

PMID42126200
PMCPMC13202701

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.