ArticleTurk gogus kalp damar cerrahisi dergisi2026
The effects of revascularization of lower extremity arterial disease on cardiac diastolic functions.
Article in Turk gogus kalp damar cerrahisi dergisi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Lower extremity arterial disease (LEAD) is a systemic atherosclerotic condition associated with increased arterial stiffness, impaired ventricular-arterial coupling, and a higher prevalence of left ventricular diastolic dysfunction (LVDD). Although endovascular revascularization improves limb perfusion, its early effects on echocardiographic indices of LVDD function and their clinical significance remain unclear. This study aimed to evaluate early changes in selected echocardiographic indices of LVDD function following successful revascularization in patients with LEAD. Methods: This prospective single-center study included 74 patients who underwent endovascular revascularization for aortoiliac or femoropopliteal disease. Transthoracic echocardiography was performed 24-48 hours before and 48-120 hours after the intervention. Diastolic indices, including e' velocity, E/e' ratio, isovolumetric relaxation time (IVRT), and IVRT/TE-e' ratio, were measured according to American Society of Echocardiography/EACVI guidelines. Longitudinal changes were analyzed using linear mixed-effects models incorporating lesion location and lesion laterality as covariates. Results: Statistically significant early changes were observed in selected diastolic parameters following revascularization. Mitral annular e' velocity increased from 7.91±2.43 to 8.69±2.35 cm/s (p=0.036), while the E/e' ratio decreased from 8.97±2.44 to 7.53±2.27 (p<0.001). IVRT (p=0.029) and the IVRT/TE-e' ratio (p=0.018) also decreased significantly. No changes were observed in blood pressure, heart rate, or left ventricular systolic function. Lesion location did not influence changes in e' velocity or E/e' ratio; however, aortoiliac disease was associated with a greater reduction in the IVRT/TE-e' ratio (p=0.021). Lesion laterality did not affect diastolic outcomes. Conclusion: Successful endovascular revascularization in patients with LEAD was associated with early changes in selected echocardiographic indices of LVDD. The clinical significance of these changes and whether they translate into long-term outcomes warrant further investigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.