ArticleIntestinal Failure (New York, N.Y.)
Nutritional status and outcomes throughout the intestinal transplant journey: Experience from the Cambridge Intestinal Transplant Unit.
Article in Intestinal Failure (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Guidance on the optimum nutritional management of patients receiving intestinal transplants (ITx) is limited. We aimed to i) describe the nutritional management of adult ITx patients in the immediate post-ITx period and ii) examine nutritional status using BMI across the ITx journey. Methods: A retrospective analysis included all adult-recipients of an intestine-containing graft at Addenbrooke's Hospital, Cambridge between 2007 and 2024. Data collected included nutritional routes immediately post-ITx (parenteral nutrition-PN, enteral nutrition-EN and oral feeding-OF) and BMI at ITx and 1 yr post-ITx. Associations between baseline BMI (at-ITx) and 1 yr post-transplant (1yr-ITx) were examined using logistic-regression for the risk of being overweight-obese at 1yr-Tx (BMI:<25 vs. ≥25 kg/m Results: 166 patients (median age 45 yrs (IQR: 34-53), and 49% female) were included in the study. Duration of PN, EN, and time to OF post-ITx was 24 days (IQR: 14-35); 38days (IQR: 15-82), 13 days (IQR: 9-24), respectively. Median weight loss 3 months post-ITx was 9% of Tx-weight, reducing to 2% at 6 months. In logistic-regression, baseline-BMI (<25 kg/m Conclusion: Our study shows that i) weight loss occurs within the first 3 months post-ITx, though mostly re-gained within 6months; ii) post-MVTx oral diet is initiated by 2 weeks; and iii) baseline BMI is the only significant predictor of 1 yr post-ITx BMI. However, 1 in 4 ITx patients with a healthy baseline BMI were observed to become overweight or obese at 1 yr. Further research is required to elucidate what mechanisms lead to the development of obesity after transplant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.