Evidence map›Paper›PMID 42125680›Full record

ArticleProgress in rehabilitation medicine2026

Relationship between Corticosteroid Dose and Physical Performance after HSCT: A Prospective Cohort Study.

Nobuyoshi Nishikado, Tatsushi Wakasugi, Katsuji Kaida, Atsushi Umeji, Koichiro Sota, Daiki Takemura, Naoki Sasanuma, Kyoko Yoshihara, Satoshi Yoshihara, Yuki Uchiyama and 1 more

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Article in Progress in rehabilitation medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Nobuyoshi NishikadoDepartment of Rehabilitation, Hyogo Medical University Hospital, Nishinomiya, Japan.
Tatsushi WakasugiDepartment of Rehabilitation, Takarazuka University of Medical and Health Care, Takarazuka, Japan.
Katsuji KaidaDepartment of Hematology, Hyogo Medical University Hospital, Nishinomiya, Japan.
Atsushi UmejiDepartment of Rehabilitation, Hyogo Medical University Hospital, Nishinomiya, Japan.
Koichiro SotaDepartment of Physical Therapy, School of Rehabilitation, Hyogo Medical University, Kobe, Japan.
Daiki TakemuraDepartment of Rehabilitation, Hyogo Medical University Hospital, Nishinomiya, Japan.
Naoki SasanumaDepartment of Rehabilitation, Hyogo Medical University Hospital, Nishinomiya, Japan.
Kyoko YoshiharaDepartment of Hematology, Hyogo Medical University Hospital, Nishinomiya, Japan.
Satoshi YoshiharaDepartment of Hematology, Hyogo Medical University Hospital, Nishinomiya, Japan.
Yuki UchiyamaDepartment of Rehabilitation Medicine, School of Medicine, Hyogo Medical University, Nishinomiya, Japan.
Kazuhisa DomenDepartment of Rehabilitation Medicine, School of Medicine, Hyogo Medical University, Nishinomiya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to prospectively investigate the factors affecting the diminished ability of patients to stand up following hematopoietic stem cell transplantation (HSCT). Methods: Fifty patients were enrolled in the study. Pre- and post-HSCT physical performance was assessed using the Short Physical Performance Battery (SPPB). Post-HSCT physical performance decline was defined as a decrease of at least 1 point in the SPPB chair rise score at hospital discharge compared with the pre-HSCT score. Factors associated with this decline were analyzed using multiple logistic regression. Results: A functional decline in the ability to stand up post-HSCT was noted. The total corticosteroid dose (odds ratio, 1.03, 95% confidence interval 1.00-1.05) showed an independent association with physical performance decline post-HSCT. Conclusions: The total corticosteroid dose is a valuable predictor of physical performance decline post-HSCT. Therefore, standing up movements should be evaluated cautiously in patients who are expected to receive high corticosteroid doses for the treatment of acute graft-versus-host disease or HSCT regimens.

Indexed as

glucocorticoid-induced muscle atrophyhematopoietic stem cell transplantationrehabilitationshort physical performance batterystanding ability

Identifiers

PMID42125680
PMCPMC13158704

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.