Machine Learning Model Predicts New-Onset Lower Extremity Deep Vein Thrombosis After Pelvic Fracture Surgery and Targeted Diagnosis.

Background: Postoperative new-onset deep vein thrombosis (PNO-DVT) is a common and serious complication after pelvic fracture surgery, significantly affecting recovery and quality of life. Traditional risk assessment tools lack precision, whereas machine learning offers improved predictive capability. This study evaluated machine learning models for predicting PNO-DVT following pelvic fracture surgery. Methods: Clinical data from 745 patients treated between 2016 and 2019 were analyzed. Demographic characteristics, laboratory indicators, surgical variables, and scoring systems were collected. Univariate logistic regression, LASSO regression, and multivariate logistic regression identified 12 independent risk factors. The dataset was split 7:3 into training and test sets. Six machine learning models (logistic regression, SVM, random forest, XGBoost, LightGBM, and AdaBoost) were constructed. Results: Univariate analysis identified GGT, HDL-C, ApoB, TCO Conclusion: Machine learning (particularly XGBoost) provides effective prediction of PNO-DVT after pelvic fracture surgery. Key predictors such as age, intraoperative blood loss, and BMI enable accurate risk stratification and support early preventive intervention.