Evidence map›Paper›PMID 42125488›Full record

ArticleGeriatric orthopaedic surgery & rehabilitation2026

Association Between Multimorbidity and Walking Independence After Total Knee Arthroplasty in Adults Aged ≥80 Years: A Retrospective Cohort Study.

Makoto Asaeda, Yukio Mikami, Atsuo Nakamae, Tomoyuki Nakasa, Akinori Nekomoto, Noriaki Maeda, Kiyo Ueda, Takeya Araki, Nobuo Adachi

Abstract read
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Article in Geriatric orthopaedic surgery & rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Makoto AsaedaDivision of Rehabilitation, Department of Clinical Practice and Support, Hiroshima University Hospital, Hiroshima, Japan.ORCID https://orcid.org/0000-0001-9323-8146
Yukio MikamiDepartment of Rehabilitation Medicine, Hiroshima University Hospital, Hiroshima, Japan.
Atsuo NakamaeDepartment of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Tomoyuki NakasaDepartment of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Akinori NekomotoDepartment of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Noriaki MaedaFaculty of Sport Sciences, School of Sport and Sciences, Waseda University, Saitama, Japan.
Kiyo UedaDepartment of Rehabilitation Medicine, Hiroshima University Hospital, Hiroshima, Japan.
Takeya ArakiDepartment of Rehabilitation Medicine, Hiroshima University Hospital, Hiroshima, Japan.
Nobuo AdachiDepartment of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The demand for total knee arthroplasty, an established treatment for advanced knee osteoarthritis, is anticipated to increase among individuals aged ≥80 years. Given the high prevalence of multimorbidity among older adults in Japan, in this study, we aimed to elucidate the relationship between multimorbidity and post-operative walking independence in this demographic. Methods: This retrospective cohort study included patients who underwent total knee arthroplasty for knee osteoarthritis between October 2023 and September 2024; those who underwent other surgeries or had significant mobility limitations were excluded. Patients aged ≥80 years with a Charlson Comorbidity Index of ≥2 were categorized into the "older patients with multimorbidity" group. The primary outcome was walking independence, which was assessed using the Functional Ambulation Category. Demographic and clinical variables were evaluated as potential confounders. Statistical tests included Student's Results: Thirteen and 42 patients were classified as "older patients with multimorbidity" and controls, respectively. Significant intergroup differences were observed in age, height, weight, and hemoglobin levels but not in the length of hospital stay and overall outcomes. Functional Ambulation Category scores declined postoperatively in both groups, with no significant intergroup difference in independent walking ability. Hierarchical multiple regression analysis of pooled data revealed no significant association between age or multimorbidity and walking independence at discharge. Conclusion: The findings indicate that age and multimorbidity are not primary determinants of post-operative walking independence. Individualized rehabilitation may improve recovery outcomes, underscoring the potential benefits of standardizing postoperative care for older patients with multimorbidity who have undergone total knee arthroplasty.

Indexed as

multimorbidityolder adultsrehabilitationtotal knee arthroplastywalking independence

Identifiers

PMID42125488
PMCPMC13158508

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.