Evidence map›Paper›PMID 42125482›Full record

ArticleERJ open research2026

Bronchiectasis in Italy: an analysis of the EMBARC registry.

Stefano Aliberti, Andrea Gramegna, Edoardo Simonetta, Alessandro De Angelis, Mattia Nigro, Anna Stainer, Francesco Amati, Salvatore Battaglia, Giovanni Sotgiu, Federico Dente and 17 more

Abstract read
In one paragraph

Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Stefano AlibertiDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID https://orcid.org/0000-0002-0090-4531
Andrea GramegnaDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0003-2315-5737
Edoardo SimonettaDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Alessandro De AngelisDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID https://orcid.org/0009-0004-3544-0361
Mattia NigroDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID https://orcid.org/0000-0003-4735-823X
Anna StainerDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID https://orcid.org/0000-0002-8875-2252
Francesco AmatiDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Salvatore BattagliaDivision of Respiratory Diseases, Dipartimento di Promozione della Salute, Materno Infantile, Medicina Interna e Specialistica di Eccellenza "G. D'Alessandro" (PROMISE), Giaccone University Hospital, University of Palermo, Palermo, Italy.ORCID https://orcid.org/0000-0002-2867-917X
Giovanni SotgiuDepartment of Medical, Clinical Epidemiology and Medical Statistics Unit, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.ORCID https://orcid.org/0000-0002-1600-4474
Federico DenteRespiratory Pathophysiology Unit, Department of Surgery, Medicine, Molecular Biology and Critical Care, University of Pisa, Pisa, Italy.
Paola FaverioSchool of Medicine and Surgery, Università degli Studi di Milano-Bicocca, Milan, Italy.ORCID https://orcid.org/0000-0002-0360-1237
Oriol SibilaRespiratory Department, Hospital Clínic, University of Barcelona, IDIBAPS, CIBERES, Barcelona, Spain.
Michal ShteinbergPulmonology Institute, Carmel Medical Center, Haifa, Israel.ORCID https://orcid.org/0000-0002-0432-3398
Montserrat VendrellDepartment of Pulmonology, Dr Trueta University Hospital, Girona Biomedical Research Institute (IDIBGI)-CERCA, University of Girona, CIBERES, Girona, Spain.
Katerina DimakouRespiratory Department and Bronchiectasis Unit, "SOTIRIA" General Hospital of Chest Diseases, Athens, Greece.
Adelina AmorimPulmonology Department, Centro Hospitalar Universitário São João and Faculty of Medicine, University of Porto, Porto, Portugal.
Eva PolverinoPneumology Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, CIBERES, Barcelona, Spain.
Sermin BorekciDepartment of Pulmonology Diseases, Cerrahpasa Medical Faculty, Istanbul University - Cerrahpasa, Istanbul, Turkey.
Eleanor GeradaDepartment of Respiratory Medicine, Mater Dei Hospital, Msida, Malta.
Jennifer PollockDivision of Respiratory Medicine and Gastroenterology, University of Dundee, Dundee, UK.
Kara RobertsonDivision of Respiratory Medicine and Gastroenterology, University of Dundee, Dundee, UK.
Veronica PolelliDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID https://orcid.org/0009-0006-8095-4251
Martina SantambrogioDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Mariangela RetucciDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Donatella NobileAssociazione Italiana Bronchiettasie, Milan, Italy.
James D ChalmersDivision of Respiratory Medicine and Gastroenterology, University of Dundee, Dundee, UK.
Francesco BlasiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0002-2285-9970

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bronchiectasis is a complex disease with geographical variability in its presentation and management. Despite the growing contribution of international registries, real-world data on the Italian bronchiectasis population remain limited. The objective of the present study was to describe the demographic, clinical, microbiological, functional and treatment characteristics of Italian patients with bronchiectasis and to compare them with those of patients from other Southern European countries. Methods: This was a secondary analysis of adults from 18 Italian centres included in the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) registry, with comparisons made to patients in Spain, Greece, Portugal, Turkey, Israel and Malta (Southern European countries). Demographics, comorbidities, exacerbation history, spirometry, microbiology and treatment patterns were evaluated. Results: Among 1657 Italian patients, the majority were female (70.5%) with a median age of 65 years, with high rates of idiopathic bronchiectasis (55.4%) and preserved lung function. Compared with other Southern European countries (n=2638), Italian patients had lower disease severity (median Bronchiectasis Severity Index: 6 Conclusions: These findings may reflect earlier referral, diagnostic preferences or structural differences in care delivery in Italy compared with other Southern European countries. This work lays the foundation for tailored national strategies and future longitudinal studies. The largest bronchiectasis cohort ever studied in Italy reveals unique clinical traits and highlights key differences from other Southern European countries, and provides real-world data to shape better care models and guide future research.

Identifiers

PMID42125482
PMCPMC13158980

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.