Evidence map›Paper›PMID 42125246›Full record

ArticlePeerJ2026

Intestinal transit time phenotype is not transferred through gut microbiota transplantation.

Anna Pii Hjørne, Chiara H Moretti, Thomas U Greiner, Nicola Procházková, Henrik M Roager, Martin Steen Mortensen, Fredrik Bäckhed, Tine Rask Licht, Martin F Laursen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna Pii HjørneNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0009-0001-5513-6576
Chiara H MorettiDepartment of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden.
Thomas U GreinerDepartment of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-9086-3667
Nicola ProcházkováDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Frederiksberg, Denmark.
Henrik M RoagerNovo Nordisk Foundation Microbiome Health Initiative, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0002-2504-8313
Martin Steen MortensenNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0001-5483-7533
Fredrik BäckhedNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Tine Rask LichtNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0002-6399-9574
Martin F LaursenNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal transit time (TT) varies considerably between healthy individuals and affects gut microbiota composition and activity. Whether differences in the gut microbiota composition also affect the TT is not well elucidated. In this study, we conducted two animal experiments to explore causality between the gut microbiota and TT. In the first experiment, we transplanted two groups of female germ-free (GF) Swiss-Webster mice with fecal material from two healthy human donors with fast and slow TT phenotypes. Following transplantation with human feces, we observed a decrease in TT for both groups of GF recipient mice (from 300 min to 167 min, 95% CI: ±45; and from 369

Indexed as

Fecal Microbiota TransplantationGastrointestinal MicrobiomeGastrointestinal TransitAnimalsFecesFemaleGerm-Free LifeHumansLoperamideMiceMice, Inbred C57BLPhenotypeLoperamideAnimal modelFecal microbiota transplantationGut microbiotaIntestinal transit timeLoperamide

Identifiers

PMID42125246
PMCPMC13159732

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.