ArticleNeuroscience applied2026
Neural correlates of cognitive improvement over time in patients newly diagnosed with bipolar disorder.
Article in Neuroscience applied, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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11 authors.
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Abstract
There is currently no known effective long-term treatment for cognitive impairments in bipolar disorder (BD) and understanding of the neurobiological mechanisms underlying cognitive impairments in BD is lacking. Identifying potential biomarkers for cognitive improvement is essential to aid targeted interventions. This study investigates the neural correlates of cognitive improvement versus lack of improvement over time in BD. Forty-six patients newly diagnosed with BD who recently began treatment in a specialized outpatient clinic and 38 healthy control individuals (HC) were assessed with a battery of neuropsychological tests and a verbal n-back working memory test during functional magnetic resonance imaging (fMRI) at baseline and follow-up (mean: 15 months). Patients were divided into two groups: those who improved cognitively over time, defined as global cognition change
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