Evidence map›Paper›PMID 42125188›Full record

ReviewSports medicine and health science2026

Evaluating the effectiveness of blood flow restriction training in older adults: An overview of systematic reviews.

Victor S de Queiros, Nicholas Rolnick, Jason R Jaggers, Igor H Fortunato, Nailton José Brandão de Albuquerque Filho, Jozilma de Medeiros Gonzaga, Maria Goretti da Cunha Lisboa, Luke Hughes

Abstract readReview
In one paragraph

Review in Sports medicine and health science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Victor S de QueirosDepartment of Physical Education, State University of Paraíba (UEPB), Campina Grande, PB, Brazil.
Nicholas RolnickThe BFR PROS, New York, NY, USA.
Jason R JaggersDepartment of Health and Sport Sciences, University of Louisville, Louisville, KY, USA.
Igor H FortunatoDepartment of Physical Education, State University of Paraíba (UEPB), Campina Grande, PB, Brazil.
Nailton José Brandão de Albuquerque FilhoDepartment of Physical Education, State University of Paraíba (UEPB), Campina Grande, PB, Brazil.
Jozilma de Medeiros GonzagaDepartment of Physical Education, State University of Paraíba (UEPB), Campina Grande, PB, Brazil.
Maria Goretti da Cunha LisboaDepartment of Physical Education, State University of Paraíba (UEPB), Campina Grande, PB, Brazil.
Luke HughesDepartment of Sport Exercise and Rehabilitation, Northumbria University, Newcastle upon Tyne, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To synthesize evidence from systematic reviews on the effects of blood flow restriction (BFR) training on muscle strength, hypertrophy, and functional performance in older adults. Methods: An umbrella review was conducted after a comprehensive search in PubMed, Scopus, SPORTDiscus, and Web of Science until June 17, 2025. Eligible studies were systematic reviews, with or without meta-analyses, examining low-load BFR training in adults aged ≥ 50 years. Outcomes included muscle strength, hypertrophy, and physical function. Study selection and data extraction were performed independently by two reviewers, and methodological quality was assessed using AMSTAR 2. Results: Twenty-three systematic reviews comprising 53 unique trials were included. Meta-analyses consistently indicated that BFR training promotes hypertrophy comparable to high-load resistance training (HL-RT) and superior to low-load training without BFR. Evidence on strength is mixed: some meta-analyses found gains similar to HL-RT, others reported inferior or superior results. Nevertheless, the majority of evidence suggests that BFR provides greater strength improvements compared to low-load training without BFR. Findings on functional performance were inconsistent. All reviews were rated as low or critically low in methodological quality. Across comparisons, heterogeneity and recurring methodological limitations-such as inadequate blinding and allocation concealment-were noted in primary studies. Conclusion: BFR training is a promising approach to enhance muscle strength and hypertrophy in older adults, but evidence certainty is limited by methodological weaknesses in both trials and reviews. Well-designed, high-quality studies are needed to confirm these effects and support clinical implementation.

Indexed as

AgingExerciseFunctional performanceMuscle hypertrophyMuscle strength

Identifiers

PMID42125188
PMCPMC13159444

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.