Evidence map›Paper›PMID 42125181›Full record

ReviewSports medicine and health science2026

Modified constraint-induced movement therapy for lower extremity intervention on patients with stroke: A Scoping Review.

Liping Zhou, Huaide Chu, Manting Cao, Nur Arzuar Abdul Rahim, Hazwani Ahmad Yusof, Ying Hou

Abstract readReview
In one paragraph

Review in Sports medicine and health science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liping ZhouDepartment of Community Health, Advanced Medical and Dental Institute, University Sains Malaysia, 13200 Kepala Batas, Pulau Pinang, Malaysia.
Huaide ChuThe Fourth People's Hospital of Kunshan, Lujia Town, Kunshan City, Jiangsu Province 215331, China.
Manting CaoDepartment of Community Health, Advanced Medical and Dental Institute, University Sains Malaysia, 13200 Kepala Batas, Pulau Pinang, Malaysia.
Nur Arzuar Abdul RahimDepartment of Clinical Medicine, Advanced Medical and Dental Institute, University Sains Malaysia, 13200 Kepala Batas, Pulau Pinang, Malaysia.
Hazwani Ahmad YusofDepartment of Community Health, Advanced Medical and Dental Institute, University Sains Malaysia, 13200 Kepala Batas, Pulau Pinang, Malaysia.
Ying HouThe Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou 215008, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Stroke is the main cause of long-term disability, burdening people and healthcare systems. In stroke patients, modified Constraint-Induced Movement Therapy (mCIMT) may improve lower extremity function. Protocol variability complicates efficacy evaluation. Objectives: For stroke patients' lower extremity rehabilitation, examine mCIMT safety and effectiveness and identify important protocol components for motor recovery augmentation. Methods: An extensive PubMed, Web of Science, Scopus, and PEDro search found clinical studies on mCIMT for lower extremity mobility impairments in adult stroke patients published between January 1, 2000, and November 30, 2023. Constraints, doses, transfer packages, and outcome measures analyzed heterogeneity and study classifications appraised quality. Results: 36 trials with 931 stroke victims were examined. Heterogeneity prevented clear results on the best mCIMT methods. Studies show that mCIMT improves motor function, functional mobility, balance, lower limb strength, weight-bearing, and walking ability with minor side effects. Physical restraint devices may be unsafe and painful. For safety, behavioral limitations are advised. Instead of training length, task repetitions are a better indication of training intensity and can decrease training time. Transfer packages help transfer training gains to daily activities and preserve long-term effects, as shown by better real-world walking habits and functional mobility during follow-up. Conclusions: mCIMT is safe and effective for stroke lower extremity rehabilitation. Behavioral limitations, a specified dose of task repetitions, and patient-specific transfer packages are recommended for mCIMT. Standardizing methods and finding appropriate component combinations to overcome heterogeneity and improve clinical applicability and patient outcomes require further study.

Indexed as

Lower extremityModified constraint-induced movement therapyMotor dysfunctionStroke

Identifiers

PMID42125181
PMCPMC13159450

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.