Evidence map›Paper›PMID 42125164›Full record

ArticleClinical case reports2026

B-Lymphoblastic Leukemia With Isolated Central Nervous System Relapse Mimicking a Vestibular Schwannoma.

Jun Yen Ng, Shivendra T Lalloo, Samuel Milliken, Mark N Polizzotto

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jun Yen NgDepartment of Haematology Canberra Hospital Canberra Australia.ORCID https://orcid.org/0000-0002-7995-4696
Shivendra T LallooDepartment of Medical Imaging Canberra Hospital Canberra Australia.
Samuel MillikenDepartment of Haematology St Vincent's Hospital Sydney Australia.
Mark N PolizzottoDepartment of Haematology Canberra Hospital Canberra Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The central nervous system (CNS) is the most common site of extramedullary relapse in acute lymphoblastic leukemia (ALL). However, the diagnosis may be challenging due to its protean manifestations. A 64-year-old male reported right-sided hearing loss with intermittent bilateral occipitotemporal headaches during a clinic follow-up for Ph + B-ALL. His yearling and neurological symptoms persisted, with two unremarkable MRI brains. However, a repeat MRI showed findings suspicious for a vestibular schwannoma. Isolated CNS relapse of B-ALL was subsequently confirmed on lumbar puncture. He received intrathecal and dasatinib therapy, which was complicated by cytomegalovirus (CMV) colitis and

Indexed as

B‐lymphoblastic leukemiaCMV infectionCNS relapsetyrosine kinase inhibitor

Identifiers

PMID42125164
PMCPMC13158867

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.