Evidence map›Paper›PMID 42125088›Full record

ArticleInternational journal of nanomedicine2026

Synergistic Neuroprotection of Fe

Ying-Ying Huang, Li-Hong Gui, Wen-Xi Yu, Rui Tao, Zhi-Heng Zhu, Jing-Jing Li, Yi-Ning Zhao, Xing-Yu Zhang, Yi-Zhuo Zhang, Yue Liu and 1 more

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Article in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ying-Ying HuangGraduate School, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Li-Hong GuiDepartment of Rehabilitation medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, 201318, People's Republic of China.
Wen-Xi YuGraduate School, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.ORCID 0009-0005-9407-2367
Rui TaoGraduate School, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Zhi-Heng ZhuDepartment of Rehabilitation medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, 201318, People's Republic of China.
Jing-Jing LiDepartment of Rehabilitation medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, 201318, People's Republic of China.
Yi-Ning ZhaoDepartment of Rehabilitation medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, 201318, People's Republic of China.
Xing-Yu ZhangGraduate School, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Yi-Zhuo ZhangGraduate School, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Yue LiuDepartment of Rehabilitation medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, 201318, People's Republic of China.
Xia BiGraduate School, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.ORCID 0000-0002-4834-6954

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ischemic stroke (IS) accompanied by reperfusion injury results from a cascade of events, including oxidative stress, inflammation, and neuronal apoptosis. Current therapies are limited by poor blood-brain barrier (BBB) penetration and insufficient targeting efficiency. Objective: This study developed an iTBS-Fe Methods: We constructed a therapeutic platform integrating intermittent theta burst stimulation (iTBS) with magnetic Fe Results: iTBS significantly enhanced magnetic targeting, resulting in approximately threefold greater Fe Conclusion: The iTBS-Fe

Indexed as

FerroptosisIschemic StrokeMagnetic Iron Oxide NanoparticlesMagnetite NanoparticlesNeuroprotective AgentsNF-E2-Related Factor 2Transcranial Magnetic StimulationAnimalsBlood-Brain BarrierMaleRatsRats, Sprague-DawleyMagnetite NanoparticlesNeuroprotective AgentsNfe2l2 protein, ratNF-E2-Related Factor 2ferroptosisischemic strokenanoparticlespolarization of microgliatranscranial magnetic stimulation

Identifiers

PMID42125088
PMCPMC13159953

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.