Evidence map›Paper›PMID 42124917›Full record

ArticleACS electrochemistry2026

Rationalized Volcano Plot in Heterogeneous Electrochemiluminescence.

Alessandro Fracassa, Michele Orza, Chiara Mariani, Claudio Ignazio Santo, Claudia Martinez Asenjo, Elisa D'Arrigo, Neso Sojic, Francesco Paolucci, Fabrizia Negri, Giovanni Valenti

Abstract read
In one paragraph

Article in ACS electrochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alessandro FracassaDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Bologna 40129, Italy.ORCID https://orcid.org/0009-0005-2685-1748
Michele OrzaDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Bologna 40129, Italy.
Chiara MarianiDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Bologna 40129, Italy.
Claudio Ignazio SantoDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Bologna 40129, Italy.ORCID https://orcid.org/0000-0003-4802-1671
Claudia Martinez AsenjoDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Bologna 40129, Italy.
Elisa D'ArrigoCNRS UMR 5255, Bordeaux INP, ENSMAC, University of Bordeaux, Pessac 33607, France.
Neso SojicCNRS UMR 5255, Bordeaux INP, ENSMAC, University of Bordeaux, Pessac 33607, France.ORCID https://orcid.org/0000-0001-5144-1015
Francesco PaolucciDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Bologna 40129, Italy.ORCID https://orcid.org/0000-0003-4614-8740
Fabrizia NegriDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Bologna 40129, Italy.ORCID https://orcid.org/0000-0002-0359-0128
Giovanni ValentiDepartment of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Bologna 40129, Italy.ORCID https://orcid.org/0000-0002-6223-2072

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The performance of electrochemically induced chemiluminescence (ECL) assays strongly depends on the stability of electrogenerated coreactant radicals, which governs the spatial extension of the ECL emitting layer. This dependence is even more pronounced for heterogeneous bead-based ECL, where the emission efficiency is widely assumed to scale proportionally with the thickness of the ECL emitting layer. To date, however, establishing a consistent relationship between ECL intensity and radical stability has remained elusive: apparent rate constants fail to isolate intrinsic deprotonation kinetics, and the rational design of amines with long-lived radical cations remains experimentally challenging. In this work, using ECL microscopy, we address both issues by correlating the ECL intensity from individual [Ru-(bpy)

Indexed as

bead-based assayDFTECL emitting layerkineticsradical deprotonation

Identifiers

PMID42124917
PMCPMC13159797

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.