Evidence map›Paper›PMID 42124860›Full record

ArticleJBMR plus2026

Improved segmentation accuracy in high-resolution peripheral quantitative computed tomography scans of carpal bones using adaptive local thresholding.

Michael T Kuczynski, Simone Poncioni, Sarah Elmahdy, Erica Baldesarra, Philippe Zysset, Sarah L Manske, Danielle E Whittier

Abstract read
In one paragraph

Article in JBMR plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael T KuczynskiMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB, Canada.ORCID https://orcid.org/0000-0001-5671-1205
Simone PoncioniARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0009-0006-2652-4613
Sarah ElmahdyMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB, Canada.
Erica BaldesarraMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB, Canada.
Philippe ZyssetARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-4712-7047
Sarah L ManskeMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB, Canada.ORCID https://orcid.org/0000-0003-0888-9556
Danielle E WhittierMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB, Canada.ORCID https://orcid.org/0000-0003-3602-551X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The choice of segmentation method for HR-pQCT scans influences accuracy of bone microarchitecture measurements. Smaller or under-mineralized bone can present challenges in accurate extraction of bone structure using global thresholding methods, as local variations in intensity are not considered and finer structural details are not detected. This is especially important in small hand bones, where bone structure is finer, or younger populations, where bone tissue may be under mineralized. This study compared accuracy of global thresholding methods using Gaussian and Laplace-Hamming filters, and an adaptive local thresholding (AT) method in HR-pQCT scans of carpal bones. Eight ex vivo human cadaveric forearms (

Indexed as

bone microarchitecturecarpal bonesHR-pQCTsegmentationtrabecular bone

Identifiers

PMID42124860
PMCPMC13160417

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.