ArticlebioRxiv : the preprint server for biology2026
Zinc excess promotes lysosome remodeling by activating HLH-30/TFEB through the action of the high zinc sensor HIZR-1.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Zinc is an essential element that plays many roles in animals. Since excess zinc is toxic, animals have evolved sophisticated mechanisms to achieve homeostasis. A conserved mechanism is to store excess zinc in specialized lysosomes, which contributes to zinc detoxification and provides a supply when zinc becomes limiting. In
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