Evidence map›Paper›PMID 42124654›Full record

ArticlebioRxiv : the preprint server for biology2026

Optogenetic WNT signaling drives germ layer self-organization in a human gastruloid model.

Hunter J Johnson, David M McMullin, Joshua A Zimmermann, Chang N Kim, Nicole A Repina, Ritu Bhalerao, Tomasz J Nowakowski, David V Schaffer

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hunter J JohnsonDepartment of Bioengineering, University of California, Berkeley; Berkeley, California, 94720, USA.ORCID 0000-0001-8337-8428
David M McMullinDepartment of Bioengineering, University of California, Berkeley; Berkeley, California, 94720, USA.ORCID 0009-0003-5152-5747
Joshua A ZimmermannDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley; Berkeley, California, 94720, USA.
Chang N KimDepartment of Anatomy, University of California, San Francisco; San Francisco, CA, 94158, USA.ORCID 0000-0001-7921-4447
Nicole A RepinaDepartment of Bioengineering, University of California, Berkeley; Berkeley, California, 94720, USA.ORCID 0000-0003-2229-5084
Ritu BhaleraoDepartment of Bioengineering, University of California, Berkeley; Berkeley, California, 94720, USA.ORCID 0009-0001-4014-1946
Tomasz J NowakowskiDepartment of Anatomy, University of California, San Francisco; San Francisco, CA, 94158, USA.ORCID 0000-0003-2345-4964
David V SchafferDepartment of Bioengineering, University of California, Berkeley; Berkeley, California, 94720, USA.ORCID 0000-0002-9625-0121

Funding

Optogenetic Characterization and Control of Stem Cell SignalingR01NS087253 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI KANE, RAVI S., SCHAFFER, DAVID V · 2014 to 2018
$1.7M
NINDS NIH HHS R01 NS087253
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42124654
PMCPMC13160121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.