Evidence map›Paper›PMID 42124599›Full record

ArticlebioRxiv : the preprint server for biology2026

Sequence and structure of protein binding sites in RNA impact biomolecular condensates.

Sierra J Cole, Scott R Allen, Bryan B Guzmán, Yue Hu, Benjamin M Stormo, Christine A Roden, Joanne Ekena, Vita Zhang, Grace A McLaughlin, Alex W Crocker and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Sierra J ColeDuke University.ORCID 0000-0003-4748-413X
Scott R AllenUniversity of North Carolina.
Bryan B GuzmánUniversity of North Carolina.
Yue HuUniversity of North Carolina.
Benjamin M StormoDuke University.
Christine A RodenUNIV. DE MONTREAL.
Joanne EkenaDuke University.
Vita ZhangDuke University.
Grace A McLaughlinDuke University.
Alex W CrockerUniversity of Minnesota.
Alain LaederachUniversity of North Carolina at Chapel Hill.ORCID 0000-0002-5088-9907
Daniel DominguezUniversity of North Carolina at Chapel Hill.
Amy S GladfelterDuke University.

Funding

Non-coding RNA structure change in Chronic Obstructive Pulmonary DiseaseR01HL111527 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Alain T Laederach, Kevin M Weeks · 2012 to 2026
$6.6M
Cytoplasmic Organization by phase transitionsR01GM081506 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GLADFELTER, AMY S · 2010 to 2023
$4.0M
Variant induced RNA structure change in human genetic diseaseR35GM140844 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LAEDERACH, ALAIN T · 2021 to 2025
$2.1M
Organization of Syncytial CellsR35GM156800 · NIGMS · DUKE UNIVERSITY · PI Amy S Gladfelter · 2025 to 2026
$1.1M
NHLBI NIH HHS R01 HL111527NIGMS NIH HHS R01 GM081506NIGMS NIH HHS R35 GM140844NIGMS NIH HHS R35 GM156800
6 · The paper itself

Abstract

Biomolecular condensates are central to subcellular compartmentalization. Although many condensates contain and regulate RNA, research has primarily focused on protein interactions. Here, we investigate RNA-protein interactions underlying cell cycle-regulating condensates in the multinucleate fungus

Identifiers

PMID42124599
PMCPMC13160123

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.