Evidence map›Paper›PMID 42124560›Full record

ArticlebioRxiv : the preprint server for biology2026

Reverse electron transfer at mitochondrial complex I restrains dopaminergic neuron activity to promote early-life sleep in

Jeffrey B Rosa, Hayle H Kim, Jenny Luong, Jianing Yang, Peyton Yee, Allen Yan, Anyara Rodriguez, Matthew S Kayser

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jeffrey B RosaDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Hayle H KimChronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jenny LuongDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jianing YangChronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Peyton YeeDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Allen YanCollege of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA.
Anyara RodriguezDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Matthew S KayserDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Funding

Investigating sleep regulation and function during early developmentR35NS137329 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI MATTHEW S KAYSER · 2024 to 2026
$2.6M
Molecular and genetic analysis of the juvenile sleep stateR01NS120979 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI KAYSER, MATTHEW S · 2021 to 2023
$1.2M
NINDS NIH HHS R01 NS120979NINDS NIH HHS R35 NS137329
6 · The paper itself

Abstract

Sleep architecture and depth undergo profound changes across early life. In many species, including

Identifiers

PMID42124560
PMCPMC13160131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.