Evidence map›Paper›PMID 42124375›Full record

ArticleJournal of viral hepatitis2026

Long-Term Persistence of Hepatitis A Virus Immunity in Healthcare Workers Upto 25 Years After Vaccination.

Chiara Noviello, Maurizio Aricò, Francesco Livio Scazzi, Giacomo Riformato, Onofrio Florio, Alessandro Furio, Angela Maria Vittoria Larocca, Claudia Palmieri, Stefano Manzi, Michele Alberto Cantalice and 2 more

Abstract read
In one paragraph

Article in Journal of viral hepatitis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chiara NovielloInterdisciplinary Department of Medicine, Aldo Moro University of Bari, Bari, Italy.
Maurizio AricòInterdisciplinary Department of Medicine, Aldo Moro University of Bari, Bari, Italy.ORCID https://orcid.org/0000-0002-1908-6671
Francesco Livio ScazziInterdisciplinary Department of Medicine, Aldo Moro University of Bari, Bari, Italy.
Giacomo RiformatoInterdisciplinary Department of Medicine, Aldo Moro University of Bari, Bari, Italy.
Onofrio FlorioInterdisciplinary Department of Medicine, Aldo Moro University of Bari, Bari, Italy.
Alessandro FurioControl Room Unit, Bari Policlinico General Hospital, Bari, Italy.
Angela Maria Vittoria LaroccaControl Room Unit, Bari Policlinico General Hospital, Bari, Italy.
Claudia PalmieriInterdisciplinary Department of Medicine, Aldo Moro University of Bari, Bari, Italy.
Stefano ManziInterdisciplinary Department of Medicine, Aldo Moro University of Bari, Bari, Italy.
Michele Alberto CantaliceControl Room Unit, Bari Policlinico General Hospital, Bari, Italy.
Silvio TafuriInterdisciplinary Department of Medicine, Aldo Moro University of Bari, Bari, Italy.
Pasquale StefanizziInterdisciplinary Department of Medicine, Aldo Moro University of Bari, Bari, Italy.ORCID https://orcid.org/0000-0002-3279-0196

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis A virus (HAV) remains globally endemic, particularly in populations with limited sanitation and poses risks to travellers and healthcare personnel. Although vaccination provides long-term protection, data on the duration of immunity in occupationally exposed groups are limited. We conducted a prospective cohort study among healthcare personnel and medical students vaccinated with either a monovalent HAV vaccine (Havrix, Avaxim) or a combined HAV/HBV vaccine (Twinrix) between 1996 and 2003 at Bari University Hospital, Italy. Vaccination records were verified, and serum anti-HAV IgG concentrations were quantified using CMIA (ARCHITECT HAVAb-IgG). Statistical analyses included Student's t-test, χ

Indexed as

Health PersonnelHepatitis AHepatitis A AntibodiesHepatitis A VaccinesHepatitis A virusAdultFemaleHepatitis B VaccinesHumansImmunoglobulin GItalyMaleMiddle AgedProspective StudiesStudents, MedicalTime FactorsHepatitis A AntibodiesHepatitis A VaccinesHepatitis B VaccinesImmunoglobulin GtwinrixVaccines, Combinedcombined HAV/HBV vaccinehealthcare workershepatitis a viruslong‐term immunityvaccine durability

Identifiers

PMID42124375
PMCPMC13168780

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.