Evidence map›Paper›PMID 42124065›Full record

ArticleNutrients2026

Supercritical CO

Serena Recalchi, Beatrice Mengoni, Barbara Scaglia, Marilena Esposito, Emiliano Montalesi, Valeria Manganelli, Gloria Riitano, Elena Fasciolo, Tuba Rana Caglar, Daniela Caissutti and 6 more

Abstract read
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Serena RecalchiDepartment of Experimental Medicine, Sapienza University of Rome, 00100 Rome, Italy.
Beatrice MengoniDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 00100 Rome, Italy.ORCID 0009-0005-5245-1684
Barbara ScagliaDepartment of Agricultural and Environmental Sciences Production, Landscape, Agroenergy (DiSAA), University of Milan, 20100 Milan, Italy.ORCID 0000-0003-2207-1232
Marilena EspositoDepartment of Agricultural and Environmental Sciences Production, Landscape, Agroenergy (DiSAA), University of Milan, 20100 Milan, Italy.
Emiliano MontalesiDepartment of Oncology and Molecular Medicine, ISS Rome, 00161 Rome, Italy.ORCID 0000-0001-8363-6052
Valeria ManganelliDepartment of Experimental Medicine, Sapienza University of Rome, 00100 Rome, Italy.
Gloria RiitanoDepartment of Experimental Medicine, Sapienza University of Rome, 00100 Rome, Italy.
Elena FascioloDepartment of Experimental Medicine, Sapienza University of Rome, 00100 Rome, Italy.ORCID 0009-0000-9868-3265
Tuba Rana CaglarDepartment of Experimental Medicine, Sapienza University of Rome, 00100 Rome, Italy.ORCID 0000-0002-8771-8036
Daniela CaissuttiDepartment of Experimental Medicine, Sapienza University of Rome, 00100 Rome, Italy.ORCID 0000-0002-5054-8061
Camilla MoliterniDepartment of Experimental Medicine, Sapienza University of Rome, 00100 Rome, Italy.
Federica ArmeliDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 00100 Rome, Italy.ORCID 0000-0002-4981-3374
Rita BusinaroDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 00100 Rome, Italy.ORCID 0000-0002-7890-8524
Roberta MisasiDepartment of Experimental Medicine, Sapienza University of Rome, 00100 Rome, Italy.ORCID 0000-0002-1181-6190
Maurizio SoriceDepartment of Experimental Medicine, Sapienza University of Rome, 00100 Rome, Italy.ORCID 0000-0003-3534-1502
Antonella CapozziDepartment of Experimental Medicine, Sapienza University of Rome, 00100 Rome, Italy.

Funding

Ministero dell'università e della ricerca PON R&I 2014-2020 (FSE REACT-EU). 000055_21_PAF_MISASI. CUP B85F21004490001
6 · The paper itself

Abstract

BACKGROUND/

objectivesIn this study, we investigated the effect on antioxidant defenses of a tomato extract obtained by supercritical CO

methodsHuman glioblastoma astrocytoma U-373 cells were pre-treated with sCO

resultsPre-treatment with sCO

conclusionsThese findings demonstrate that sCO

Indexed as

AstrocytesInflammationOxidative StressPlant ExtractsSignal TransductionSolanum lycopersicumAntioxidantsCarbon DioxideCell Line, TumorCell SurvivalChromatography, Supercritical FluidGlutathione PeroxidaseGlutathione Peroxidase GPX1HumansLipid PeroxidationNF-E2-Related Factor 2AntioxidantsCarbon DioxideGlutathione PeroxidaseGlutathione Peroxidase GPX1NFE2L2 protein, humanNF-E2-Related Factor 2NF-kappa BPlant ExtractsReactive Oxygen SpeciesSOD1 protein, humanSuperoxide Dismutase-1nutraceuticaloxidative stresssupercritical CO2 extractiontomato extracts

Identifiers

PMID42124065
PMCPMC13165377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.