Evidence map›Paper›PMID 42123947›Full record

ArticleNutrients2026

Recalibrating Resting Energy Expenditure Prediction Equations in Asian Older Adults with Multimorbidity.

Pei San Kua, Musfirah Albakri, Su Mei Tay, Phoebe Si-En Thong, Olivia Jiawen Xia, Wendelynn Hui Ping Chua, Kevin Chong, Nicholas Wei Kiat Tan, Xin Hui Loh, Jia Hui Tan and 1 more

Abstract read
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pei San KuaSingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.ORCID 0009-0006-1064-4741
Musfirah AlbakriSingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.
Su Mei TaySingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.
Phoebe Si-En ThongSingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.
Olivia Jiawen XiaSingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.
Wendelynn Hui Ping ChuaSingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.ORCID 0009-0006-0677-7584
Kevin ChongSingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.
Nicholas Wei Kiat TanSingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.
Xin Hui LohSingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.ORCID 0009-0006-4172-8972
Jia Hui TanSingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.
Lian Leng LowSingHealth Community Hospitals, 10 Hospital Blvd, Singapore 168582, Singapore.

Funding

Singapore MOH Health Innovation (MHI) fund MH 110:12/12-30
6 · The paper itself

Abstract

BACKGROUND/

objectiveAccurate resting energy expenditure (REE) estimation is paramount for the nutritional management of older Asian adults with multimorbidity. However, standard predictive equations (PEs) lack precision for this cohort. This study aimed to recalibrate PEs using BMI-stratified, slope-only regression to enhance bedside accuracy.

methodsREE was measured via indirect calorimetry in 400 hospitalized patients (age ≥ 65). Sensitivity analyses identified significant proportional bias in existing models. Models were recalibrated and validated using 1000-iteration bootstrap resampling.

resultsStandard PEs exhibited significant bias, particularly overpredicting requirements for 68% of underweight patients. The new Singapore Older Adults Resting energy expenditure (SOAR) PE 1 (963.67 + 8.56 × weight - 5.6 × age) eliminated weight-dependent systematic errors. The recalibrated models utilizing actual body weight achieved accuracy rates of up to 64% in obese cohorts, comparable to complex adjusted-weight protocols.

conclusionsPopulation-specific recalibration is essential to mitigate the bidirectional risks of malnutrition and overfeeding in geriatric rehabilitation. The BMI-stratified multipliers provided offer a robust, clinically efficient framework for individualized nutritional care.

Indexed as

Asian PeopleBasal MetabolismEnergy MetabolismMultimorbidityAgedAged, 80 and overBody Mass IndexCalorimetry, IndirectFemaleGeriatric AssessmentHumansMaleObesityPrediction Methods, MachineRestSingaporeAsian older adultsmultimorbidityprediction equationsrecalibrationresting energy expenditure

Identifiers

PMID42123947
PMCPMC13164755

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.